Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
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Viroids: from genotype to phenotype just relying on RNA sequence and structural motifsUbiquitous presence of the hammerhead ribozyme motif along the tree of lifeThe ubiquitous hammerhead ribozymeStructure-function analysis of the ribozymes of chrysanthemum chlorotic mottle viroid: a loop-loop interaction motif conserved in most natural hammerheadsActive-Site Monovalent Cations Revealed in a 1.55-Å-Resolution Hammerhead Ribozyme StructureStructure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase functionChemistry and Biology of Self-Cleaving RibozymesThe glmS ribozyme: use of a small molecule coenzyme by a gene-regulatory RNASmall self-cleaving ribozymesMg2+ ions: do they bind to nucleobase nitrogens?The hammerhead ribozyme: structure, catalysis, and gene regulationEnhanced product stability in the hammerhead ribozyme.Structural and catalytic effects of an invariant purine substitution in the hammerhead ribozyme: implications for the mechanism of acid-base catalysis.Protein-responsive ribozyme switches in eukaryotic cells.Role of tautomerism in RNA biochemistry.Conformational heterogeneity and the determinants of tertiary stabilization in the hammerhead ribozyme from Dolichopoda cave crickets.Ground-state coordination of a catalytic metal to the scissile phosphate of a tertiary-stabilized Hammerhead ribozyme.Minimal Hammerhead Ribozymes with Uncompromised Catalytic ActivityHigh-throughput cellular RNA device engineering.Folding of the hammerhead ribozyme: pyrrolo-cytosine fluorescence separates core folding from global folding and reveals a pH-dependent conformational change.Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.Force Field for Mg(2+), Mn(2+), Zn(2+), and Cd(2+) Ions That Have Balanced Interactions with Nucleic Acids.Two Active Site Divalent Ions in the Crystal Structure of the Hammerhead Ribozyme Bound to a Transition State AnalogueLewis acid catalysis of phosphoryl transfer from a copper(II)-NTP complex in a kinase ribozyme.Three-way RNA junctions with remote tertiary contacts: a recurrent and highly versatile fold.Solving novel RNA structures using only secondary structural fragments.Nucleases: diversity of structure, function and mechanism.Viroid replication: rolling-circles, enzymes and ribozymes.Thermodynamics and kinetics of RNA tertiary structure formation in the junctionless hairpin ribozyme.Divalent Metal Ion Activation of a Guanine General Base in the Hammerhead Ribozyme: Insights from Molecular Simulations.The Hammerhead Ribozyme: A Long History for a Short RNA.Long-range tertiary interactions in single hammerhead ribozymes bias motional sampling toward catalytically active conformationsThe unforeseeable hammerhead ribozyme.A remarkably stable kissing-loop interaction defines substrate recognition by the Neurospora Varkud Satellite ribozyme.The identity of the nucleophile substitution may influence metal interactions with the cleavage site of the minimal hammerhead ribozyme.Trans-cleaving hammerhead ribozymes with tertiary stabilizing motifs: in vitro and in vivo activity against a structured viroid RNASmall Molecule Recognition Triggers Secondary and Tertiary Interactions in DNA Folding and Hammerhead Ribozyme Catalysis.Investigation of the Melting Behavior of DNA Three-Way Junctions in the Closed and Open States.
P2860
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P2860
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
@ast
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
@en
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
@nl
type
label
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
@ast
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
@en
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
@nl
altLabel
Capturing hammerhead ribozyme structures in action by modulating general base catalysis
@en
prefLabel
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
@ast
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
@en
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
@nl
P2093
P2860
P1433
P1476
Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis
@en
P2093
Monica Lares
Monika Martick
William G Scott
Young-In Chi
P2860
P356
10.1371/JOURNAL.PBIO.0060234
P407
P577
2008-09-30T00:00:00Z