Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket

Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket

Item
http://www.wikidata.org/entity/Q27652418
Structure of human ADAM-8 catalytic domain complexed with batimastatStructure-based rational design of peptide hydroxamic acid inhibitors to target tumor necrosis factor-α converting enzyme as potential therapeutics for hepatitis.ADAM17 cleaves CD16b (FcγRIIIb) in human neutrophilsADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha.Free energy calculations on snake venom metalloproteinase BaP1.A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17.Molecular basis for the mechanism of action of an anti-TACE antibody.Molecular Descriptors in Modelling the Tumour Necrosis Factor-α Converting Enzyme Inhibition Activity of Novel Tartrate-Based Analogues.
P2860

Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket

Item
http://www.wikidata.org/entity/Q27652418
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
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2008年論文
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2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Discovery of novel hydroxamate ...... optimization of the S3' pocket
@ast
Discovery of novel hydroxamate ...... optimization of the S3' pocket
@en
Discovery of novel hydroxamate ...... optimization of the S3' pocket
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type
label
Discovery of novel hydroxamate ...... optimization of the S3' pocket
@ast
Discovery of novel hydroxamate ...... optimization of the S3' pocket
@en
Discovery of novel hydroxamate ...... optimization of the S3' pocket
@nl
prefLabel
Discovery of novel hydroxamate ...... optimization of the S3' pocket
@ast
Discovery of novel hydroxamate ...... optimization of the S3' pocket
@en
Discovery of novel hydroxamate ...... optimization of the S3' pocket
@nl
P1433
P1476
P2093
P304
P31
P3181
P356
P407
P433
P478
P577
P698
P3181
P356
P1433
P1476
Discovery of novel hydroxamate ...... optimization of the S3' pocket
@en
P2093
P304
P31
P3181
P356
10.1016/J.BMCL.2008.09.045
P407
P433
P478
P577
P698