Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
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Crystal Structures of Brain Group-VIII Phospholipase A2 in Nonaged Complexes with the Organophosphorus Nerve Agents Soman and Sarin † , ‡Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabunCrystal structures of human group-VIIA phospholipase A2 inhibited by organophosphorus nerve agents exhibit non-aged complexesX-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavengerReaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-ray Structure AnalysisCocrystallization studies of full-length recombinant butyrylcholinesterase (BChE) with cocaineStructure and function of an insect -carboxylesterase ( Esterase7) associated with insecticide resistanceStructures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interfaceButyrylcholinesterase for protection from organophosphorus poisons: catalytic complexities and hysteretic behaviorA wrench in the works of human acetylcholinesterase: soman induced conformational changes revealed by molecular dynamics simulationsNerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase.Mass spectrometry method to identify aging pathways of Sp- and Rp-tabun adducts on human butyrylcholinesterase based on the acid labile P-N bondInteraction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases.Exposure to tri-o-cresyl phosphate detected in jet airplane passengers.Simultaneous measurement of tabun, sarin, soman, cyclosarin, VR, VX, and VM adducts to tyrosine in blood products by isotope dilution UHPLC-MS/MSCatalytic bioscavengers against toxic esters, an alternative approach for prophylaxis and treatments of poisonings.A high-throughput UHPLC-MS/MS method for the quantification of five aged butyrylcholinesterase biomarkers from human exposure to organophosphorus nerve agents.Online combination of reversed-phase/reversed-phase and porous graphitic carbon liquid chromatography for multicomponent separation of proteomics and glycoproteomics samples.Why does the G117H mutation considerably improve the activity of human butyrylcholinesterase against sarin? Insights from quantum mechanical/molecular mechanical free energy calculations.Novel Organophosphate Ligand O-(2-Fluoroethyl)-O-(p-Nitrophenyl)Methylphosphonate: Synthesis, Hydrolytic Stability and Analysis of the Inhibition and Reactivation of Cholinesterases.Aging mechanism of soman inhibited acetylcholinesterase.Novel selective and irreversible mosquito acetylcholinesterase inhibitors for controlling malaria and other mosquito-borne diseases.Profiling cholinesterase adduction: a high-throughput prioritization method for organophosphate exposure samples.Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study.On the Influence of the Protonation States of Active Site Residues on AChE Reactivation: A QM/MM Approach.A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase.Novel Group of AChE Reactivators-Synthesis, In Vitro Reactivation and Molecular Docking Study
P2860
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P2860
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
@ast
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
@en
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
@nl
type
label
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
@ast
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
@en
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
@nl
prefLabel
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
@ast
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
@en
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
@nl
P2093
P356
P1476
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation
@en
P2093
Emilie Gillon
Eugénie Carletti
Fredrik Ekström
Lawrence M Schopfer
Marie T Froment
Mélanie Loiodice
Oksana Lockridge
Patrick Masson
P304
P356
10.1021/JA804941Z
P407
P577
2008-11-26T00:00:00Z