Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK?

Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK?

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Ten things you should know about protein kinases: IUPHAR Review 14Halogen bonding at the active sites of human cathepsin L and MEK1 kinase: efficient interactions in different environmentsAutoDock VinaXB: implementation of XBSF, new empirical halogen bond scoring function, into AutoDock VinaSynthesis of rocaglamide hydroxamates and related compounds as eukaryotic translation inhibitors: synthetic and biological studiesDual inhibition of allosteric mitogen-activated protein kinase (MEK) and phosphatidylinositol 3-kinase (PI3K) oncogenic targets with a bifunctional inhibitorA novel role for copper in Ras/mitogen-activated protein kinase signaling.Measuring and interpreting the selectivity of protein kinase inhibitorsMolecular mechanisms of drug resistance in tyrosine kinases cAbl and cKit.Molecular recognition in chemical and biological systems.Selective, rapid and optically switchable regulation of protein function in live mammalian cells.
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Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK?

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http://www.wikidata.org/entity/Q27652938
description
2009 nî lūn-bûn
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2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2009 թվականի հունվարին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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name
Beyond the MEK-pocket: can cur ...... ist in kinases other than MEK?
@ast
Beyond the MEK-pocket: can cur ...... ist in kinases other than MEK?
@en
Beyond the MEK-pocket: can cur ...... ist in kinases other than MEK?
@nl
type
label
Beyond the MEK-pocket: can cur ...... ist in kinases other than MEK?
@ast
Beyond the MEK-pocket: can cur ...... ist in kinases other than MEK?
@en
Beyond the MEK-pocket: can cur ...... ist in kinases other than MEK?
@nl
prefLabel
Beyond the MEK-pocket: can cur ...... ist in kinases other than MEK?
@ast
Beyond the MEK-pocket: can cur ...... ist in kinases other than MEK?
@en
Beyond the MEK-pocket: can cur ...... ist in kinases other than MEK?
@nl
P1433
P1476
P2093
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P698
P3181
P356
P1433
P1476
Beyond the MEK-pocket: can cur ...... ist in kinases other than MEK?
@en
P2093
P304
P31
P3181
P356
10.1016/J.BMCL.2008.10.108
P407
P433
P478
P50
P577
P698