Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement
about
Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulationsPotent BACE-1 inhibitor design using pharmacophore modeling, in silico screening and molecular docking studiesAdvances in the identification of β-secretase inhibitors.BACE1 as a therapeutic target in Alzheimer's disease: rationale and current status.Biological and computational evaluation of resveratrol inhibitors against Alzheimer's disease.Fragment Binding to β-Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches.
P2860
Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Identification of a small mole ...... catalytic aspartate engagement
@ast
Identification of a small mole ...... catalytic aspartate engagement
@en
Identification of a small mole ...... catalytic aspartate engagement
@nl
type
label
Identification of a small mole ...... catalytic aspartate engagement
@ast
Identification of a small mole ...... catalytic aspartate engagement
@en
Identification of a small mole ...... catalytic aspartate engagement
@nl
prefLabel
Identification of a small mole ...... catalytic aspartate engagement
@ast
Identification of a small mole ...... catalytic aspartate engagement
@en
Identification of a small mole ...... catalytic aspartate engagement
@nl
P2093
P1476
Identification of a small mole ...... catalytic aspartate engagement
@en
P2093
Amy S Espeseth
Ashley A Nomland
Dennis Colussi
Georgia McGaughey
Ivory D Hills
Katherine Tugusheva
Pablo de León
Samuel L Graham
Sharie J Haugabook
P356
10.1016/J.BMCL.2008.11.027
P407
P577
2009-01-01T00:00:00Z