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Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethalityStructure of an RNA polymerase II preinitiation complex.The Structure of the TFIIH p34 Subunit Reveals a Von Willebrand Factor A Like FoldFunction of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIHNear-atomic resolution visualization of human transcription promoter opening.Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIHp8/TTDA overexpression enhances UV-irradiation resistance and suppresses TFIIH mutations in a Drosophila trichothiodystrophy model.Slowly progressing nucleotide excision repair in trichothiodystrophy group A patient fibroblasts.XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.Control of the function of the transcription and repair factor TFIIH by the action of the cochaperone Ydj1.ARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activitiesStructural basis of transcription initiation by RNA polymerase II.Analysis of Drosophila p8 and p52 mutants reveals distinct roles for the maintenance of TFIIH stability and male germ cell differentiation.Architecture of an RNA polymerase II transcription pre-initiation complex.The cryo-electron microscopy structure of human transcription factor IIH.Physical and functional interactions between Drosophila homologue of Swc6/p18Hamlet subunit of the SWR1/SRCAP chromatin-remodeling complex with the DNA repair/transcription factor TFIIH.The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH.Structures of transcription pre-initiation complex with TFIIH and Mediator.The essential and multi-functional TFIIH complex.Small molecule-based targeting of TTD-A dimerization to control TFIIH transcriptional activity represents a potential strategy for anticancer therapy
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural basis for group A trichothiodystrophy
@ast
Structural basis for group A trichothiodystrophy
@en
Structural basis for group A trichothiodystrophy
@nl
type
label
Structural basis for group A trichothiodystrophy
@ast
Structural basis for group A trichothiodystrophy
@en
Structural basis for group A trichothiodystrophy
@nl
prefLabel
Structural basis for group A trichothiodystrophy
@ast
Structural basis for group A trichothiodystrophy
@en
Structural basis for group A trichothiodystrophy
@nl
P50
P3181
P356
P1476
Structural basis for group A trichothiodystrophy
@en
P2093
Marc Vitorino
P2888
P3181
P356
10.1038/NSMB.1478
P577
2008-09-01T00:00:00Z
P5875
P6179
1037563678