The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional
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Comparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson's DiseaseSolution structure and dynamics of mouse ARMETMesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons(1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF)The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers.Characterization of the structural and functional determinants of MANF/CDNF in Drosophila in vivo modelTherapeutic efficacy of AAV8-mediated intrastriatal delivery of human cerebral dopamine neurotrophic factor in 6-OHDA-induced parkinsonian rat models with different disease progression.Widespread cortical expression of MANF by AAV serotype 7: localization and protection against ischemic brain injury.Induction profile of MANF/ARMET by cerebral ischemia and its implication for neuron protection.Molecular effects of doxycycline treatment on pterygium as revealed by massive transcriptome sequencing.Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigraUpregulation of mesencephalic astrocyte-derived neurotrophic factor in glial cells is associated with ischemia-induced glial activation.Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's diseaseFunctions for the cardiomyokine, MANF, in cardioprotection, hypertrophy and heart failure.CDNF protects the nigrostriatal dopamine system and promotes recovery after MPTP treatment in mice.Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra.Viral vector delivery of neurotrophic factors for Parkinson's disease therapy.Cerebral Dopamine Neurotrophic Factor: A Potential Therapeutic Agent for Parkinson's Disease.Mesencephalic astrocyte-derived neurotrophic factor and its role in nervous system disease.Harpagoside attenuates MPTP/MPP⁺ induced dopaminergic neurodegeneration and movement disorder via elevating glial cell line-derived neurotrophic factor.Intracellular trafficking and secretion of mouse mesencephalic astrocyte-derived neurotrophic factor.Mesencephalic astrocyte-derived neurotrophic factor (MANF), a new player in endoplasmic reticulum diseases: structure, biology, and therapeutic roles.An evolutionary perspective on the role of mesencephalic astrocyte-derived neurotrophic factor (MANF): At the crossroads of poriferan innate immune and apoptotic pathwaysRole of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity.Mechanisms of anti-inflammatory property of conserved dopamine neurotrophic factor: inhibition of JNK signaling in lipopolysaccharide-induced microglia.Downregulation of DmMANF in Glial Cells Results in Neurodegeneration and Affects Sleep and Lifespan in Drosophila melanogaster.Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Elevates Stimulus-Evoked Release of Dopamine in Freely-Moving Rats.Cerebral dopamine neurotrophic factor protects H9c2 cardiomyocytes from apoptosis.Intracellular trafficking and secretion of cerebral dopamine neurotrophic factor in neurosecretory cells.Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotectionPhotoreceptor Protection by Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF).Emerging Roles for Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) in Pancreatic Beta Cells and DiabetesAntioxidative CXXC Peptide Motif From Mesencephalic Astrocyte-Derived Neurotrophic Factor Antagonizes Programmed Cell DeathMANF Homolog Is Necessary for the Protection of Dopaminergic Neurons and ER Unfolded Protein Response
P2860
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P2860
The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional
description
2009 nî lūn-bûn
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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The structure of the conserved ...... ains why they are bifunctional
@ast
The structure of the conserved ...... ains why they are bifunctional
@en
The structure of the conserved ...... ains why they are bifunctional
@nl
type
label
The structure of the conserved ...... ains why they are bifunctional
@ast
The structure of the conserved ...... ains why they are bifunctional
@en
The structure of the conserved ...... ains why they are bifunctional
@nl
prefLabel
The structure of the conserved ...... ains why they are bifunctional
@ast
The structure of the conserved ...... ains why they are bifunctional
@en
The structure of the conserved ...... ains why they are bifunctional
@nl
P2093
P356
P1476
The structure of the conserved ...... ains why they are bifunctional
@en
P2093
Adrian Goldman
Esko Oksanen
Johan Peränen
Mart Saarma
Nisse Kalkkinen
Päivi Lindholm
Vimal Parkash
P304
P356
10.1093/PROTEIN/GZN080
P577
2009-04-01T00:00:00Z