A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch: General Architecture of the Metalloinsertion Binding Mode
about
The path for metal complexes to a DNA targetCrystal structure of Δ-[Ru(bpy)2dppz]2+ bound to mismatched DNA reveals side-by-side metalloinsertion and intercalationDouble threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine-thymine mismatchBinding of a designed anti-cancer drug to the central cavity of an RNA three-way junctionDelta chirality ruthenium 'light-switch' complexes can bind in the minor groove of DNA with five different binding modesLuminescent properties of ruthenium(II) complexes with sterically expansive ligands bound to DNA defects.An unusual ligand coordination gives rise to a new family of rhodium metalloinsertors with improved selectivity and potency.A monofunctional platinum complex coordinated to a rhodium metalloinsertor selectively binds mismatched DNA in the minor groove.Targeting DNA Mismatches with Rhodium Metalloinsertors.The many twists and turns of DNA: template, telomere, tool, and target.The importance of peripheral sequences in determining the metal selectivity of an in vitro-selected Co(2+) -dependent DNAzyme.Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA.Cell-selective biological activity of rhodium metalloinsertors correlates with subcellular localizationTowards artificial metallonucleases for gene therapy: recent advances and new perspectives.Ruthenium(II) polypyridyl complexes and DNA--from structural probes to cellular imaging and therapeutics.Finding needles in a basestack: recognition of mismatched base pairs in DNA by small molecules.Atomistic-level portrayal of drug-DNA Interplay: a history of courtships and meetings revealed by molecular simulations.Metal complex interactions with DNA.Luminescence of [Ru(bpy)2(dppz)]2+ bound to RNA mismatches.Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.[Ru(Me4phen)2dppz](2+), a Light Switch for DNA MismatchesBinding of copper(II) polypyridyl complexes to DNA and consequences for DNA-based asymmetric catalysis.Biological effects of simple changes in functionality on rhodium metalloinsertors.Metal Complexes for DNA-Mediated Charge Transport.Construction and application of a Rh-Pt DNA metalloinsertor conjugate.Targeted Chemotherapy with Metal Complexes.Rhodium metalloinsertor binding generates a lesion with selective cytotoxicity for mismatch repair-deficient cells.A Ruthenium(II) Complex as a Luminescent Probe for DNA Mismatches and Abasic Sites.A Rhodium-Cyanine Fluorescent Probe: Detection and Signaling of Mismatches in DNA.A Family of Rhodium Complexes with Selective Toxicity toward Mismatch Repair-Deficient Cancers.A survey of recent unusual high-resolution DNA structures provoked by mismatches, repeats and ligand binding
P2860
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P2860
A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch: General Architecture of the Metalloinsertion Binding Mode
description
2009 nî lūn-bûn
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2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
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name
A Bulky Rhodium Complex Bound ...... Metalloinsertion Binding Mode
@ast
A Bulky Rhodium Complex Bound ...... Metalloinsertion Binding Mode
@en
A Bulky Rhodium Complex Bound ...... Metalloinsertion Binding Mode
@nl
type
label
A Bulky Rhodium Complex Bound ...... Metalloinsertion Binding Mode
@ast
A Bulky Rhodium Complex Bound ...... Metalloinsertion Binding Mode
@en
A Bulky Rhodium Complex Bound ...... Metalloinsertion Binding Mode
@nl
prefLabel
A Bulky Rhodium Complex Bound ...... Metalloinsertion Binding Mode
@ast
A Bulky Rhodium Complex Bound ...... Metalloinsertion Binding Mode
@en
A Bulky Rhodium Complex Bound ...... Metalloinsertion Binding Mode
@nl
P2093
P2860
P3181
P356
P1433
P1476
A Bulky Rhodium Complex Bound ...... Metalloinsertion Binding Mode
@en
P2093
Brian M Zeglis
Jacqueline K Barton
Jens T Kaiser
Valérie C Pierre
P2860
P304
P3181
P356
10.1021/BI900194E
P407
P577
2009-05-26T00:00:00Z