Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity - Wikidata - wikimedia - TriplyDB

Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity

Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity

http://www.wikidata.org/entity/Q27655433

about

An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2.Pyk2 and Megakaryocytes Regulate Osteoblast Differentiation and Migration Via Distinct and Overlapping Mechanisms.Sulfoximines: a neglected opportunity in medicinal chemistry.N-cyano sulfoximines: COX inhibition, anticancer activity, cellular toxicity, and mutagenicity.Synthesis of chiral sulfoximine-based thioureas and their application in asymmetric organocatalysis.FAK inhibitors in Cancer, a patent review.Copper-Catalyzed Direct Sulfoximination of Heteroaromatic N-Oxides by Dual C-H/N-H Dehydrogenative Cross-Coupling.Access to N-cyanosulfoximines by transition metal-free iminations of sulfoxides.Copper promoted N-alkylation of sulfoximines with alkylboronic acid under mild conditions.Protein Kinase 2β Is Expressed in Neural Crest-Derived Urinary Pacemaker Cells and Required for Pyeloureteric Contraction.Sulfur Imidations by Light-Induced Ruthenium-Catalyzed Nitrene Transfer Reactions Light-Induced Ruthenium-Catalyzed Nitrene Transfer Reactions: A Photochemical Approach towards N-Acyl Sulfimides and Sulfoximines N-Alkylations ofNH-Sulfoximines andNH-Sulfondiimines with Alkyl Halides Mediated by Potassium Hydroxide in Dimethyl Sulfoxide Copper-Catalyzed Oxidative Cross-Coupling of Sulfoximines and Alkynes The Copper-Catalyzed OxidativeN-Acylation of Sulfoximines Synthesis of Sulfondiimines byN-Chlorosuccinimide-Mediated Oxidative Imination of Sulfiliminium Salts Palladium-Catalyzed CN Cross-Coupling ofN′-Monosubstituted Sulfondiimines with Aryl Bromides Synthesis of N-Methyl-2-indolyl- and N-Methyl-2-benzo[b]furyl-Substituted Sulfoximines by Pd/Cu Co-Catalyzed Domino Cross-Coupling/Cyclization Reactions

P2860

Q36390162-6BCDE831-CF23-4257-B7E6-0AE80A4E9EFD Q36767926-690B370A-D7AB-486A-A1E7-642A7C55A866 Q38128269-49CBB7A2-A2B5-4EB7-B9D2-3363E462457C Q39229336-0C269E34-F1A0-41A6-9905-054F3F8BD2EF Q41810226-3CCE7629-524A-4CC1-B782-A8C46F86CF3F Q47797785-D08D7EBA-AF38-41E6-87FA-12F87CEF2230 Q48136672-7BE15233-0210-435F-9191-0D8EFB6ABDFA Q48364779-C622A173-D180-425F-B765-EDC5EE492912 Q49790987-240A7B90-C13B-4094-846A-E1486C139435 Q50048221-38D05D9A-9CB7-4B34-8763-8864B28BDDF9 Q57404748-49A358DB-126F-4A2E-9F38-4321B1896719 Q57404759-22FD6766-EFB2-4E63-948B-205C6AD5288F Q57404768-7B8EB8A2-6FD1-4490-98E5-31AA1575A126 Q57404778-A6541865-57BA-4F35-8028-1A8BD0B903F5 Q57404787-F14A5B81-FC81-4152-9262-337D78EB32EA Q57404797-65955D7A-C391-4B40-98AF-523C3B4C9B9F Q57404803-E64EE451-6D32-495E-8675-E0E66FBCC2D6 Q57404810-C925A6E9-9125-41E4-A70B-9CF3B1F1CAB6

P2860

Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity

http://www.wikidata.org/entity/Q27655433

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Sulfoximine-substituted triflu ...... K2) show reduced hERG activity

@ast

Sulfoximine-substituted triflu ...... K2) show reduced hERG activity

@en

Sulfoximine-substituted triflu ...... K2) show reduced hERG activity

@nl

type

label

Sulfoximine-substituted triflu ...... K2) show reduced hERG activity

@ast

Sulfoximine-substituted triflu ...... K2) show reduced hERG activity

@en

Sulfoximine-substituted triflu ...... K2) show reduced hERG activity

@nl

prefLabel

Sulfoximine-substituted triflu ...... K2) show reduced hERG activity

@ast

Sulfoximine-substituted triflu ...... K2) show reduced hERG activity

@en

Sulfoximine-substituted triflu ...... K2) show reduced hERG activity

@nl

P1433

Q27655433-BCB7AA4A-A34E-43C1-AFCA-E4EAD487D7C6

P1476

Q27655433-38893265-F911-4324-99F8-86279C96D138

P2093

Q27655433-08F85056-FE99-4496-9EE8-396AEBE3FAE4

Q27655433-27401787-3610-48A7-BB10-E1A2B11F1D1D

Q27655433-2965C9FB-9FCB-4B5E-8583-165DECA755FD

Q27655433-4DB3E0C7-8729-4AEC-AB50-BA80537A63AC

Q27655433-548E8FDC-03DA-4DDA-8F4E-56B2ECA8EAE1

Q27655433-719F2CB6-E8AD-4167-8B3A-8F36D61D6041

Q27655433-8794AD1B-021E-45FA-99E8-328062CD20CB

Q27655433-9D57C7A4-459C-4B86-8CBE-38A4585FE69A

Q27655433-A9310F1E-39B7-4D19-9E0D-ADBCA0A1A874

Q27655433-AEFEF921-7F0A-49F0-A9A8-51B67989EB17

P304

Q27655433-9EA5E064-DB20-4C1B-AA3A-9C40DD089271

P31

Q27655433-46E9E044-F2F8-4192-914C-663FE3640D00

P356

Q27655433-2C9A8AA9-7F03-4C98-A346-A954A0403270

P407

Q27655433-6F3E80C0-2B0E-4AD5-B2B3-0342F1C4E7DE

P433

Q27655433-6614494E-75EE-4D72-AC79-6221CE22C4B8

P478

Q27655433-F2B8CB34-6CE3-43AF-819C-67C43423F934

P577

Q27655433-425948F4-A73F-48B7-916D-61FEA8B74BCB

P698

Q27655433-FA7C1BF8-B0F1-4ECD-83AE-56F61AF8C762

P356

J.BMCL.2009.04.093

P1433

Bioorganic & Medicinal Chemistry Letters

P1476

Sulfoximine-substituted triflu ...... K2) show reduced hERG activity

@en

P2093

Amy Baumann

http://www.w3.org/2001/XMLSchema#string

Angel Guzman-Perez

http://www.w3.org/2001/XMLSchema#string

Anil Mistry

http://www.w3.org/2001/XMLSchema#string

Daniel P Walker

http://www.w3.org/2001/XMLSchema#string

Daniel W Kung

http://www.w3.org/2001/XMLSchema#string

Janet A Houser

http://www.w3.org/2001/XMLSchema#string

Jason Boer

http://www.w3.org/2001/XMLSchema#string

Jian-Cheng Li

http://www.w3.org/2001/XMLSchema#string

Leonard Buckbinder

http://www.w3.org/2001/XMLSchema#string

Li Xing

http://www.w3.org/2001/XMLSchema#string

P304

3253-8

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.BMCL.2009.04.093

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

19

http://www.w3.org/2001/XMLSchema#string

P577

2009-06-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

19428251

http://www.w3.org/2001/XMLSchema#string