Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
about
The retinoid X receptors and their ligandsStructure of a thyroid hormone receptor DNA-binding domain homodimer bound to an inverted palindrome DNA response elementDesign, sythesis and evaluation of a series of 3- or 4-alkoxy substituted phenoxy derivatives as PPARs agonists.Pharmacophore modeling improves virtual screening for novel peroxisome proliferator-activated receptor-gamma ligands.Structure-based virtual screening and discovery of New PPARδ/γ dual agonist and PPARδ and γ agonists.Effects of Tocotrienols on Insulin Secretion-Associated Genes Expression of Rat Pancreatic Islets in a Dynamic Culture.Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ.Activation of PPARδ: from computer modelling to biological effects.Multitargeted bioactive ligands for PPARs discovered in the last decade.Rationally designed PPARδ-specific agonists and their therapeutic potential for metabolic syndromeLigand- and structure-based drug design strategies and PPARδ/α selectivity.Molecular features related to the binding mode of PPARδ agonists from QSAR and docking analyses.Exploring molecular fingerprints of selective PPARδ agonists through comparative and validated chemometric techniques.Identifying Activity Cliff Generators of PPAR Ligands Using SAS Maps.Role of physicochemical properties in the activation of peroxisome proliferator-activated receptor δ.SAR and Computer-Aided Drug Design Approaches in the Discovery of Peroxisome Proliferator-Activated ReceptorγActivators: A Perspective
P2860
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P2860
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
@ast
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
@en
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
@nl
type
label
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
@ast
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
@en
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
@nl
prefLabel
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
@ast
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
@en
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
@nl
P2093
P3181
P1476
Identification of a PPARdelta agonist with partial agonistic activity on PPARgamma
@en
P2093
Alex Zhang
Athena Sudom
Jinsong Liu
Karen Siegler
Malgorzata Wanska
Marc Labelle
Martin Harrison
Michael Dore
P304
P3181
P356
10.1016/J.BMCL.2009.04.151
P407
P577
2009-07-01T00:00:00Z