Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
about
NMR solution structure of human vaccinia-related kinase 1 (VRK1) reveals the C-terminal tail essential for its structural stability and autocatalytic activityCrystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanismRegulation of AMP-activated protein kinase by natural and synthetic activatorsCurrent understanding of metformin effect on the control of hyperglycemia in diabetesAbscisic acid perception and signaling: structural mechanisms and applicationsAMP-activated protein kinase: a target for drugs both ancient and modernNutritional control of growth and development in yeastA conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulationAn inhibited conformation for the protein kinase domain of theSaccharomyces cerevisiaeAMPK homolog Snf1Structural basis for compound C inhibition of the human AMP-activated protein kinase α2 subunit kinase domainThe Structure of Arabidopsis thaliana OST1 Provides Insights into the Kinase Regulation Mechanism in Response to Osmotic StressStructural basis for basal activity and autoactivation of abscisic acid (ABA) signaling SnRK2 kinasesStructural Basis for the Regulation of Maternal Embryonic Leucine Zipper KinaseAMP-activated protein kinase undergoes nucleotide-dependent conformational changesStructural basis of AMPK regulation by small molecule activatorsThe structures of the kinase domain and UBA domain of MPK38 suggest the activation mechanism for kinase activityConserved regulatory elements in AMPKSUMOylation regulates the SNF1 protein kinase.AMP-activated protein kinase: a cellular energy sensor that comes in 12 flavoursDeciphering the structural basis of eukaryotic protein kinase regulationIn Vitro Anti-Echinococcal and Metabolic Effects of Metformin Involve Activation of AMP-Activated Protein Kinase in Larval Stages of Echinococcus granulosusAMPK: a nutrient and energy sensor that maintains energy homeostasisEffects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation.Structural basis and functions of abscisic acid receptors PYLs.The dynamical mechanism of auto-inhibition of AMP-activated protein kinaseExposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase.β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK).Structural basis of the regulatory mechanism of the plant CIPK family of protein kinases controlling ion homeostasis and abiotic stressNutrient sensing and signaling in the yeast Saccharomyces cerevisiae.Ab initio modeling and experimental assessment of Janus Kinase 2 (JAK2) kinase-pseudokinase complex structure.Pemetrexed indirectly activates the metabolic kinase AMPK in human carcinomas.Alterations at dispersed sites cause phosphorylation and activation of SNF1 protein kinase during growth on high glucoseAMPK inhibition in health and disease.Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseasesPolarized activities of AMPK and BRSK in primary hippocampal neurons.Subunit and domain requirements for adenylate-mediated protection of Snf1 kinase activation loop from dephosphorylationMolecular mechanism for inhibition of a critical component in the Arabidopsis thaliana abscisic acid signal transduction pathways, SnRK2.6, by protein phosphatase ABI1Tuning protein autoinhibition by domain destabilizationCarbon source metabolism and its regulation in cancer cells.Regulation of NAD(P)H oxidases by AMPK in cardiovascular systems
P2860
Q24301389-EBFD9649-FCAE-4755-9113-0E4090F70CEFQ24609716-99F45A25-DE07-4DEB-8CA9-066912FAA9C3Q26767334-8DC518FB-BFB6-4884-99B9-C4960C73A602Q26770236-9CDAA5FB-0E4D-460D-8CA2-88857A11A170Q26822490-A6D60C23-69E1-4A0E-8A72-15F02C93FEF0Q26864424-67B96D32-3153-48B6-868E-A94B28BB854EQ27003312-CFD1982E-F686-4074-8068-22626FADF4E4Q27659450-FBA85AFA-AB89-4F41-B61E-F094F1E6C3FBQ27664320-C868CD24-66ED-4F25-B983-D58C4F2B65A5Q27667722-903EA4B9-A854-4843-917F-51174FA8BEEAQ27674795-4A1C656C-50BC-452A-8AE3-B4B97F66F7BDQ27676137-A2ED0D4A-F2D4-4FD2-AFFA-62537EBAD186Q27679427-72BA6D88-27FC-4DB6-BEC2-52B8E32A6C2DQ27679458-910697B4-9CCE-4E11-AADE-2A6076A19542Q27680957-38D27851-125B-4EB8-B12E-6B5B75C9C142Q27681770-140AC9E0-7068-44FE-B3E4-77EF70925978Q27684811-FF0588EA-117B-4B78-B1FC-6E245C0E3B9AQ27932790-A363D5AF-9895-40AD-915A-5BF75E01C31AQ28074581-CA2102EA-83DE-4458-B652-8021F7A72DECQ28534399-068FDD87-27A9-4848-BF1D-9D5F8A051CFEQ28547202-8F7435A4-D31F-40DA-BFF0-3672B12FA219Q29615410-4EBA7F0D-01D0-45B9-A5CE-E41BC9E59B8AQ30395205-E25EDEE0-B9CB-4743-BC6F-A4393D89A02BQ30905499-298B3034-A3E2-4DBA-BB66-C6E9F14130E3Q33981218-F77D4842-4157-45A7-AECF-8711567FCBF6Q34236772-173A3BE4-B929-410A-A23B-FA2328A33DBBQ34320385-F5B21D28-EA15-47D9-839A-6DCBECC139DEQ34408770-B5D52230-A30A-478F-9C32-4FBCE54DBF96Q34548962-C74F123B-A819-4F6C-9DD6-24100B056649Q34671755-118ADDE2-8077-4140-B6A0-28F6BB1498F0Q34686810-6986DB2C-357B-4F29-ABA6-1F304EA9135EQ35067886-CA8B32DD-D28C-4CC7-9C22-2237B47D7B93Q35094436-FC1E9F02-16D5-47EC-BEA6-8FA12A432858Q35224775-142A6615-F90E-4F40-AA3C-599780B79A04Q35621982-FB52E2D5-D333-48F6-A32E-775F1E31112EQ35639796-E62BF5AA-5A45-4650-83D7-FC4976C89DB4Q35643892-3DF2B1E6-CE9D-4D34-92C2-95500D76BD57Q35693138-6BB87D73-C934-4ACF-A71E-431C4CDD94BBQ35861635-F1BC2008-DD30-46A2-B1DB-A23CEA493380Q35925959-1D384CFD-8E99-4042-AC42-47FD7D7F90CD
P2860
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
@ast
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
@en
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
@nl
type
label
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
@ast
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
@en
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
@nl
prefLabel
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
@ast
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
@en
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
@nl
P2093
P3181
P356
P1433
P1476
Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
@en
P2093
Jia-Wei Wu
Li-Sha Zheng
Shu-Tao Xie
Yuan-Yuan Zhang
Zhi-Hao Jiao
Zhi-Xin Wang
P2888
P304
P3181
P356
10.1038/NATURE08075
P407
P50
P577
2009-05-27T00:00:00Z
P5875
P6179
1001821123