Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate
about
First Three-Dimensional Structure of Toxoplasma gondii Thymidylate Synthase–Dihydrofolate Reductase: Insights for Catalysis, Interdomain Interactions, and Substrate ChannelingThe Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking InvestigationsDevelopments in diagnosis and antileishmanial drugs.Crystallization and preliminary crystallographic studies of dihydrofolate reductase-thymidylate synthase from Trypanosoma cruzi, the Chagas disease pathogen.Understanding the molecular mechanism of substrate channeling and domain communication in protozoal bifunctional TS-DHFR.Pharmacoinformatic Study on the Selective Inhibition of the Protozoan Dihydrofolate Reductase Enzymes.Selective peptide inhibitors of bifunctional thymidylate synthase-dihydrofolate reductase from Toxoplasma gondii provide insights into domain-domain communication and allosteric regulation.Formation of catalytically active cross-species heterodimers of thymidylate synthase from Plasmodium falciparum and Plasmodium vivax.
P2860
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P2860
Structures of dihydrofolate reductase-thymidylate synthase of Trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structures of dihydrofolate re ...... trimetrexate and methotrexate
@ast
Structures of dihydrofolate re ...... trimetrexate and methotrexate
@en
Structures of dihydrofolate re ...... trimetrexate and methotrexate
@nl
type
label
Structures of dihydrofolate re ...... trimetrexate and methotrexate
@ast
Structures of dihydrofolate re ...... trimetrexate and methotrexate
@en
Structures of dihydrofolate re ...... trimetrexate and methotrexate
@nl
prefLabel
Structures of dihydrofolate re ...... trimetrexate and methotrexate
@ast
Structures of dihydrofolate re ...... trimetrexate and methotrexate
@en
Structures of dihydrofolate re ...... trimetrexate and methotrexate
@nl
P1476
Structures of dihydrofolate re ...... trimetrexate and methotrexate
@en
P2093
Norbert Schormann
P304
P356
10.1107/S090744490901230X
P577
2009-07-01T00:00:00Z