Structural studies on the reaction of isopenicillin N synthase with a sterically demanding depsipeptide substrate analogue
about
The crystal structure of an LLL-configured depsipeptide substrate analogue bound to isopenicillin N synthaseIsopenicillin N synthase binds δ-(L-α-aminoadipoyl)-L-cysteinyl-D-thia-allo-isoleucine through both sulfur atomsThe interaction of isopenicillin N synthase with homologated substrate analogues δ-(L-α-aminoadipoyl)-L-homocysteinyl-D-Xaa characterised by protein crystallographyThe crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding siteThe enzymes of β-lactam biosynthesis.Substrate activation by iron superoxo intermediates.Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases.Cyclobutanone Analogues of β-Lactam Antibiotics: β-Lactamase Inhibitors with Untapped Potential?Terminally Truncated Isopenicillin N Synthase Generates a Dithioester Product: Evidence for a Thioaldehyde Intermediate during Catalysis and a New Mode of Reaction for Non-Heme Iron Oxidases.Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis
P2860
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P2860
Structural studies on the reaction of isopenicillin N synthase with a sterically demanding depsipeptide substrate analogue
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural studies on the reac ...... epsipeptide substrate analogue
@ast
Structural studies on the reac ...... epsipeptide substrate analogue
@en
Structural studies on the reac ...... epsipeptide substrate analogue
@nl
type
label
Structural studies on the reac ...... epsipeptide substrate analogue
@ast
Structural studies on the reac ...... epsipeptide substrate analogue
@en
Structural studies on the reac ...... epsipeptide substrate analogue
@nl
prefLabel
Structural studies on the reac ...... epsipeptide substrate analogue
@ast
Structural studies on the reac ...... epsipeptide substrate analogue
@en
Structural studies on the reac ...... epsipeptide substrate analogue
@nl
P2093
P356
P1433
P1476
Structural studies on the reac ...... epsipeptide substrate analogue
@en
P2093
Annaleise R Howard-Jones
Ian J Clifton
Jack E Baldwin
Jeanette E Stok
Peter J Rutledge
Robert M Adlington
P304
P356
10.1002/CBIC.200900080
P577
2009-08-17T00:00:00Z