Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250

Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250

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http://www.wikidata.org/entity/Q27656622
Antigenic peptide trimming by ER aminopeptidases--insights from structural studiesStructural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1A Common Single Nucleotide Polymorphism in Endoplasmic Reticulum Aminopeptidase 2 Induces a Specificity Switch That Leads to Altered Antigen ProcessingA Naturally Variable Residue in the S1 Subsite of M1 Family Aminopeptidases Modulates Catalytic Properties and Promotes Functional SpecializationStereoselective Synthesis of α-Amino-C-phosphinic Acids and DerivativesThe Plasmodium falciparum malaria M1 alanyl aminopeptidase (PfA-M1): insights of catalytic mechanism and function from MD simulationsProposed Bioactive Conformations of Opiorphin, an Endogenous Dual APN/NEP Inhibitor.An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling.Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases.Engagement of the S1, S1' and S2' subsites drives efficient catalysis of peptide bond hydrolysis by the M1-family aminopeptidase from Plasmodium falciparum.Glu121-Lys319 salt bridge between catalytic and N-terminal domains is pivotal for the activity and stability of Escherichia coli aminopeptidase N.Contribution of Delta-Opioid Receptors to Pathophysiological Events Explored by Endogenous Enkephalins.
P2860

Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250

Item
http://www.wikidata.org/entity/Q27656622
description
2009 nî lūn-bûn
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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structure of aminopeptidase N ...... minophosphinic inhibitor PL250
@ast
Structure of aminopeptidase N ...... minophosphinic inhibitor PL250
@en
Structure of aminopeptidase N ...... minophosphinic inhibitor PL250
@nl
type
label
Structure of aminopeptidase N ...... minophosphinic inhibitor PL250
@ast
Structure of aminopeptidase N ...... minophosphinic inhibitor PL250
@en
Structure of aminopeptidase N ...... minophosphinic inhibitor PL250
@nl
prefLabel
Structure of aminopeptidase N ...... minophosphinic inhibitor PL250
@ast
Structure of aminopeptidase N ...... minophosphinic inhibitor PL250
@en
Structure of aminopeptidase N ...... minophosphinic inhibitor PL250
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
Structure of aminopeptidase N ...... minophosphinic inhibitor PL250
@en
P2093
P304
P31
P356
P433
P478
P577
P698
P921