The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
about
Members of the DAN family are BMP antagonists that form highly stable noncovalent dimersThe DAN family: modulators of TGF-β signaling and beyondThe T?R-I Pre-Helix Extension Is Structurally Ordered in the Unbound Form and Its Flanking Prolines Are Essential for BindingStructure of Myostatin·Follistatin-like 3Structure of Protein Related to Dan and Cerberus: Insights into the Mechanism of Bone Morphogenetic Protein AntagonismThe clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformedInsights into the potential function and membrane organization of the TP0435 (Tp17) lipoprotein from Treponema pallidum derived from structural and biophysical analysesStructural basis for potency differences between GDF8 and GDF11.Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody.Cytotoxic aggregation and amyloid formation by the myostatin precursor proteinThe C313Y Piedmontese mutation decreases myostatin covalent dimerisation and stability.Inhibin at 90: from discovery to clinical application, a historical reviewTargeting senescent cells enhances adipogenesis and metabolic function in old ageBiochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future InvestigationDevelopment of a small-molecule screening method for inhibitors of cellular response to myostatin and activin A.Extracellular Regulation of Myostatin: A Molecular Rheostat for Muscle Mass.Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (-)-epicatechin in healthy volunteers.Alternative binding modes identified for growth and differentiation factor-associated serum protein (GASP) family antagonism of myostatin.Energy deprivation alters in a leptin- and cortisol-independent manner circulating levels of activin A and follistatin but not myostatin in healthy males.Characterization of follistatin-type domains and their contribution to myostatin and activin A antagonism.Virtual High-Throughput Screening To Identify Novel Activin Antagonists.Analysis of the interaction between heparin and follistatin and heparin and follistatin-ligand complexes using surface plasmon resonance.Myostatin Attenuation In Vivo Reduces Adiposity, but Activates AdipogenesisTransforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding.Quantification of GDF11 and Myostatin in Human Aging and Cardiovascular Disease.Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism.TGF-β antagonists: same knot, but different hold.Myostatin stimulates, not inihibits, C2C12 myoblast proliferation.Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists.Activin receptor antagonists for cancer-related anemia and bone disease.Structural and Dynamic Characterization of the C313Y Mutation in Myostatin Dimeric Protein, Responsible for the "Double Muscle" Phenotype in Piedmontese Cattle.Heparin, Heparan Sulphate and the TGF-β Cytokine Superfamily.Structural Biology and Evolution of the TGF-β FamilyExpression and purification of recombinant protein related to DAN and cerberus (PRDC).Follistatin N terminus differentially regulates muscle size and fat in vivo.Analysis and identification of the Grem2 heparin/heparan sulfate-binding motif.Inhibition of GDF8 (Myostatin) accelerates bone regeneration in diabetes mellitus type 2Identification of ligand-selective peptidic ActRIIB-antagonists using phage display technologySmall molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiation.cDNA structure and the effect of fasting on myostatin expression in walking catfish (Clarias macrocephalus, Günther 1864).
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P2860
The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The structure of myostatin:fol ...... tilization and heparin binding
@ast
The structure of myostatin:fol ...... tilization and heparin binding
@en
The structure of myostatin:fol ...... tilization and heparin binding
@nl
type
label
The structure of myostatin:fol ...... tilization and heparin binding
@ast
The structure of myostatin:fol ...... tilization and heparin binding
@en
The structure of myostatin:fol ...... tilization and heparin binding
@nl
prefLabel
The structure of myostatin:fol ...... tilization and heparin binding
@ast
The structure of myostatin:fol ...... tilization and heparin binding
@en
The structure of myostatin:fol ...... tilization and heparin binding
@nl
P2093
P2860
P356
P1433
P1476
The structure of myostatin:fol ...... tilization and heparin binding
@en
P2093
Alexandra C McPherron
Carlis A Rejon
Daniel J Bernard
Jennifer N Cash
P2860
P304
P356
10.1038/EMBOJ.2009.205
P407
P577
2009-07-30T00:00:00Z