The Structure of the Dizinc Subclass B2 Metallo- -Lactamase CphA Reveals that the Second Inhibitory Zinc Ion Binds in the Histidine Site
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Carbapenems: past, present, and futureBiochemical and Structural Characterization of the Subclass B1 Metallo- -Lactamase VIM-4Mutagenesis of Zinc Ligand Residue Cys221 Reveals Plasticity in the IMP-1 Metallo- -Lactamase Active SiteStructure of Apo- and Monometalated Forms of NDM-1—A Highly Potent Carbapenem-Hydrolyzing Metallo-β-LactamaseOvercoming differences: The catalytic mechanism of metallo-β-lactamasesBiapenem inactivation by B2 metallo β-lactamases: energy landscape of the post-hydrolysis reactionsBiochemical characteristics of New Delhi metallo-β-lactamase-1 show unexpected difference to other MBLsCharacterization of a novel Zn²⁺-dependent intrinsic imipenemase from Pseudomonas aeruginosaEvolution of Metallo-β-lactamases: Trends Revealed by Natural Diversity and in vitro EvolutionStructural phylogeny by profile extraction and multiple superimposition using electrostatic congruence as a discriminator.Biapenem inactivation by B2 metallo β-lactamases: energy landscape of the hydrolysis reaction.Deep Sequencing of Random Mutant Libraries Reveals the Active Site of the Narrow Specificity CphA Metallo-β-Lactamase is Fragile to Mutations.Expanding the Repertoire of Carbapenem-Hydrolyzing Metallo-ß-Lactamases by Functional Metagenomic Analysis of Soil Microbiota.Role of Non-Active-Site Residue Trp-93 in the Function and Stability of New Delhi Metallo-β-Lactamase 1.Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes.Crystal Structure of the Metallo-β-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site.Metallo-β-lactamase structure and function.A variety of roles for versatile zinc in metallo-β-lactamases.Crystal structures reveal metal-binding plasticity at the metallo-β-lactamase active site of PqqB from Pseudomonas putida.Biochemical characterization of Sfh-I, a subclass B2 metallo-beta-lactamase from Serratia fonticola UTAD54.Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family.The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing β-Lactamases of Potential Clinical Relevance.Kinetic Studies on CphA Mutants Reveal the Role of the P158-P172 Loop in Activity versus Carbapenems.The CphAII protein from Aquifex aeolicus exhibits a metal-dependent phosphodiesterase activity.Identification and characterization of an unusual metallo-β-lactamase from Serratia proteamaculans.The use of SWATH to analyse the dynamic changes of bacterial proteome of carbapanemase-producing Escherichia coli under antibiotic pressure.Inhibition of a cold-active alkaline phosphatase by imipenem revealed by in silico modeling of metallo-β-lactamase active sites.
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P2860
The Structure of the Dizinc Subclass B2 Metallo- -Lactamase CphA Reveals that the Second Inhibitory Zinc Ion Binds in the Histidine Site
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2009 nî lūn-bûn
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2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
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2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
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2009年论文
@wuu
name
The Structure of the Dizinc Su ...... on Binds in the Histidine Site
@ast
The Structure of the Dizinc Su ...... on Binds in the Histidine Site
@en
The Structure of the Dizinc Su ...... on Binds in the Histidine Site
@nl
type
label
The Structure of the Dizinc Su ...... on Binds in the Histidine Site
@ast
The Structure of the Dizinc Su ...... on Binds in the Histidine Site
@en
The Structure of the Dizinc Su ...... on Binds in the Histidine Site
@nl
prefLabel
The Structure of the Dizinc Su ...... on Binds in the Histidine Site
@ast
The Structure of the Dizinc Su ...... on Binds in the Histidine Site
@en
The Structure of the Dizinc Su ...... on Binds in the Histidine Site
@nl
P2093
P2860
P50
P3181
P356
P1476
The Structure of the Dizinc Su ...... on Binds in the Histidine Site
@en
P2093
Charlotte Willmann
Heinrich Delbrück
Kurt M V Hoffmann
Michaël B Kupper
Philipp Schlömer
Rainer Fischer
P2860
P304
P3181
P356
10.1128/AAC.00288-09
P407
P577
2009-10-01T00:00:00Z