Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases
about
Activation of EGFR by small compounds through coupling the generation of hydrogen peroxide to stable dimerization of Cu/Zn SOD1.Structures of a putative ζ-class glutathione S -transferase from the pathogenic fungus Coccidioides immitisThe fine-tuning of TRAF2-GSTP1-1 interaction: effect of ligand binding and in situ detection of the complexTargeting Glutathione S-transferase M4 in Ewing sarcoma18F-glutathione conjugate as a PET tracer for imaging tumors that overexpress L-PGDS enzyme.8-Methoxypsoralen is a competitive inhibitor of glutathione S-transferase P1-1Bivalent enzyme inhibitors discovered using dynamic covalent chemistry.PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS.Prediction of substrates for glutathione transferases by covalent docking.A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts.Investigation of brain tumors using (18)F-fluorobutyl ethacrynic amide and its metabolite with positron emission tomographyIrreversible binding of an anticancer compound (BI-94) to plasma proteins.7-Nitro-4-(phenylthio)benzofurazan is a potent generator of superoxide and hydrogen peroxidePleiotropic functions of glutathione S-transferase PScreening and discovery of nitro-benzoxadiazole compounds activating epidermal growth factor receptor (EGFR) in cancer cells.Proteomic and functional analyses reveal pleiotropic action of the anti-tumoral compound NBDHEX in Giardia duodenalis.Human cytosolic glutathione-S-transferases: quantitative analysis of expression, comparative analysis of structures and inhibition strategies of isozymes involved in drug resistance.Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine.Biochemical Characterization of the Detoxifying Enzyme Glutathione Transferase P1-1 from the Camel Camelus Dromedarius.Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines.The FAD-dependent glycerol-3-phosphate dehydrogenase of Giardia duodenalis: an unconventional enzyme that interacts with the g14-3-3 and it is a target of the antitumoral compound NBDHEX.Cytokine-Induced Killer Cells Modulates Resistance to Cisplatin in the A549/DDP Cell Line.Dual-target cancer theranostic for glutathione S-transferase and hypoxia-inducible factor-1α inhibition.6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio) hexanol: a promising new anticancer compound.Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases.A covalent G-site inhibitor for glutathione S-transferase Pi (GSTP1-1).Glutathione analogues as substrates or inhibitors that discriminate between allozymes of the MDR-involved human glutathione transferase P1-1.
P2860
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P2860
Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural basis for the bindi ...... man glutathione s-transferases
@ast
Structural basis for the bindi ...... man glutathione s-transferases
@en
Structural basis for the bindi ...... man glutathione s-transferases
@nl
type
label
Structural basis for the bindi ...... man glutathione s-transferases
@ast
Structural basis for the bindi ...... man glutathione s-transferases
@en
Structural basis for the bindi ...... man glutathione s-transferases
@nl
prefLabel
Structural basis for the bindi ...... man glutathione s-transferases
@ast
Structural basis for the bindi ...... man glutathione s-transferases
@en
Structural basis for the bindi ...... man glutathione s-transferases
@nl
P2093
P1433
P1476
Structural basis for the bindi ...... man glutathione s-transferases
@en
P2093
Anna Maria Caccuri
Carlo Lo Sterzo
Flavio Scaloni
Giorgio Federici
Luca Federici
Silvia Pezzola
P304
P356
10.1158/0008-5472.CAN-09-1314
P407
P577
2009-10-15T00:00:00Z