Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors

Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors

Item
http://www.wikidata.org/entity/Q27657743
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-MetSPSB1 promotes breast cancer recurrence by potentiating c-MET signaling.Araguspongine C induces autophagic death in breast cancer cells through suppression of c-Met and HER2 receptor tyrosine kinase signaling.Comprehensive Molecular Characterization of Papillary Renal-Cell CarcinomaNovel EGFR (T790M)-cMET dual inhibitors: putative therapeutic agents for non-small-cell lung cancer.Probing Mechanisms of CYP3A Time-Dependent Inhibition Using a Truncated Model System.Insight into the key features for ligand binding in Y1230 mutated c-Met kinase domain by molecular dynamics simulations.Design Some New Type-I c-met Inhibitors Based on Molecular Docking and Topomer CoMFA Research.Pharmacophore modeling and virtual screening studies to identify new c-Met inhibitors.Expeditious one-pot synthesis of C3-piperazinyl-substituted quinolines: key precursors to potent c-Met inhibitors.
P2860

Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors

Item
http://www.wikidata.org/entity/Q27657743
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年论文
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name
Discovery and optimization of ...... ine series of c-Met inhibitors
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Discovery and optimization of ...... ine series of c-Met inhibitors
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Discovery and optimization of ...... ine series of c-Met inhibitors
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Discovery and optimization of ...... ine series of c-Met inhibitors
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Discovery and optimization of ...... ine series of c-Met inhibitors
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Discovery and optimization of ...... ine series of c-Met inhibitors
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Discovery and optimization of ...... ine series of c-Met inhibitors
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Discovery and optimization of ...... ine series of c-Met inhibitors
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Discovery and optimization of ...... ine series of c-Met inhibitors
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Discovery and optimization of ...... ine series of c-Met inhibitors
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10.1016/J.BMCL.2009.09.096
P407
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