Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations
about
Electron Microscopy: From 2D to 3D Images with Special Reference to MuscleSingle-Particle Cryo-EM of the Ryanodine Receptor Channel in an Aqueous EnvironmentSingle-particle cryo-EM of calcium release channels: structural validationDisease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interfaceStructural and functional conservation of key domains in InsP3 and ryanodine receptorsInherited dysfunction of sarcoplasmic reticulum Ca2+ handling and arrhythmogenesisDo's and don'ts of cryo-electron microscopy: a primer on sample preparation and high quality data collection for macromolecular 3D reconstruction.FRET-based localization of fluorescent protein insertions within the ryanodine receptor type 1.Characterization of a novel mutation in the cardiac ryanodine receptor that results in catecholaminergic polymorphic ventricular tachycardiaShort-coupled polymorphic ventricular tachycardia at rest linked to a novel ryanodine receptor (RyR2) mutation: leaky RyR2 channels under non-stress conditions.Myoplasmic resting Ca2+ regulation by ryanodine receptors is under the control of a novel Ca2+-binding region of the receptor.Mapping the ryanodine receptor FK506-binding protein subunit using fluorescence resonance energy transfer.Ryanodine receptors: structure, expression, molecular details, and function in calcium release.FRET-based trilateration of probes bound within functional ryanodine receptors.Single-particle cryo-EM of the ryanodine receptor channel in an aqueous environment.Regulation of ryanodine receptor RyR2 by protein-protein interactions: prediction of a PKA binding site on the N-terminal domain of RyR2 and its relation to disease causing mutationsThe H29D Mutation Does Not Enhance Cytosolic Ca2+ Activation of the Cardiac Ryanodine ReceptorCrystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant.Abnormal termination of Ca2+ release is a common defect of RyR2 mutations associated with cardiomyopathiesModeling a ryanodine receptor N-terminal domain connecting the central vestibule and the corner clamp region.Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor/Ca2+ release channel (RyR1): sites and nature of oxidative modification.Conformational dynamics inside amino-terminal disease hotspot of ryanodine receptorUnreported intrinsic disorder in proteins: Building connections to the literature on IDPs.Ryanodine receptor mutations in arrhythmia: The continuing mystery of channel dysfunction.IP(3) receptors: toward understanding their activation.Beamline 08ID-1, the prime beamline of the Canadian Macromolecular Crystallography Facility.The structural biology of ryanodine receptors.Ryanodine receptors: structure and function.Themes and variations in ER/SR calcium release channels: structure and function.Ryanodine receptor calcium release channels: lessons from structure-function studies.TRP channels as sensors of oxygen availability.Investigating the inter-subunit/subdomain interactions and motions relevant to disease mutations in the N-terminal domain of ryanodine receptors by molecular dynamics simulation.Characterization of ryanodine receptor type 1 single channel activity using "on-nucleus" patch clampSubtype-selective regulation of IP(3) receptors by thimerosal via cysteine residues within the IP(3)-binding core and suppressor domainThe Cytoplasmic Region of Inner Helix S6 Is an Important Determinant of Cardiac Ryanodine Receptor Channel Gating.Bioinformatic mapping and production of recombinant N-terminal domains of human cardiac ryanodine receptor 2Roles of the NH2-terminal domains of cardiac ryanodine receptor in Ca2+ release activation and termination.Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.Selecting ions by size in a calcium channel: the ryanodine receptor case study.CPVT-associated cardiac ryanodine receptor mutation G357S with reduced penetrance impairs Ca2+ release termination and diminishes protein expression.
P2860
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P2860
Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal structures of the N-te ...... nsights into disease mutations
@ast
Crystal structures of the N-te ...... nsights into disease mutations
@en
Crystal structures of the N-te ...... nsights into disease mutations
@nl
type
label
Crystal structures of the N-te ...... nsights into disease mutations
@ast
Crystal structures of the N-te ...... nsights into disease mutations
@en
Crystal structures of the N-te ...... nsights into disease mutations
@nl
prefLabel
Crystal structures of the N-te ...... nsights into disease mutations
@ast
Crystal structures of the N-te ...... nsights into disease mutations
@en
Crystal structures of the N-te ...... nsights into disease mutations
@nl
P1433
P1476
Crystal structures of the N-te ...... nsights into disease mutations
@en
P2093
Filip Van Petegem
Paolo Antonio Lobo
P304
P356
10.1016/J.STR.2009.08.016
P577
2009-11-11T00:00:00Z