SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination
about
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65Synaptic vesicle trafficking and Parkinson's diseaseAutoregulation of Parkin activity through its ubiquitin-like domainStructure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionRBR E3 ubiquitin ligases: new structures, new insights, new questionsThe three 'P's of mitophagy: PARKIN, PINK1, and post-translational modificationsParkin structure and functionA bacterial antirepressor with SH3 domain topology mimics operator DNA in sequestering the repressor DNA recognition helixSolution structure of the N-terminal domain of DC-UbP/UBTD2 and its interaction with ubiquitinSolution structure of the E3 ligase HOIL-1 Ubl domainDistinct Ubiquitin Binding Modes Exhibited by SH3 Domains: Molecular Determinants and Functional ImplicationsStructure of parkin reveals mechanisms for ubiquitin ligase activationParkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality controlMutation in the SYNJ1 gene associated with autosomal recessive, early-onset ParkinsonismRecruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fissionPINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65Human autoantibodies to amphiphysin induce defective presynaptic vesicle dynamics and composition.Vesicle uncoating regulated by SH3-SH3 domain-mediated complex formation between endophilin and intersectin at synapsesAutoinhibition of endophilin in solution via interdomain interactions.Structural basis of membrane bending by the N-BAR protein endophilinThe BAR Domain Superfamily Proteins from Subcellular Structures to Human DiseasesSynucleins regulate the kinetics of synaptic vesicle endocytosis.Parkin regulates kainate receptors by interacting with the GluK2 subunitDNAJC6 Mutations Associated With Early-Onset Parkinson's Disease.Upregulation of Parkin in endophilin mutant mice.USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkinThe E3 ubiquitin ligase parkin is recruited to the 26 S proteasome via the proteasomal ubiquitin receptor Rpn13Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells.Human ASPL/TUG interacts with p97 and complements the proteasome mislocalization of a yeast ubx4 mutant, but not the ER-associated degradation defect.Is amyloid binding alcohol dehydrogenase a drug target for treating Alzheimer's disease?Membrane trafficking in neuronal maintenance and degeneration.The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizuresNew approaches for studying synaptic development, function, and plasticity using Drosophila as a model systemParkin Deficiency Reduces Hippocampal Glutamatergic Neurotransmission by Impairing AMPA Receptor Endocytosis.Synaptic dysfunction in genetic models of Parkinson's disease: a role for autophagy?Ubiquitin links to cytoskeletal dynamics, cell adhesion and migration.Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.Regulation of Parkin E3 ubiquitin ligase activity.An emerging role of PARK2 in cancer.A new pathway for mitochondrial quality control: mitochondrial-derived vesicles.
P2860
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P2860
SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
SH3 domains from a subset of B ...... kin in synaptic ubiquitination
@ast
SH3 domains from a subset of B ...... kin in synaptic ubiquitination
@en
SH3 domains from a subset of B ...... kin in synaptic ubiquitination
@nl
type
label
SH3 domains from a subset of B ...... kin in synaptic ubiquitination
@ast
SH3 domains from a subset of B ...... kin in synaptic ubiquitination
@en
SH3 domains from a subset of B ...... kin in synaptic ubiquitination
@nl
prefLabel
SH3 domains from a subset of B ...... kin in synaptic ubiquitination
@ast
SH3 domains from a subset of B ...... kin in synaptic ubiquitination
@en
SH3 domains from a subset of B ...... kin in synaptic ubiquitination
@nl
P2093
P50
P921
P3181
P1433
P1476
SH3 domains from a subset of B ...... kin in synaptic ubiquitination
@en
P2093
Carol X-Q Chen
Edna Matta Camacho
Jean-François Trempe
Karl Grenier
Peter S McPherson
P304
P3181
P356
10.1016/J.MOLCEL.2009.11.021
P577
2009-12-25T00:00:00Z