Crystal structure of the carnitine transporter and insights into the antiport mechanism
about
Insights to ligand binding to the monoamine transporters-from homology modeling to LeuBAT and dDATNonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substratesHow LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transportersStrategies of bacterial over expression of membrane transporters relevant in human health: the successful case of the three members of OCTN subfamilyUnveiling the Mechanism of Arginine Transport through AdiC with Molecular Dynamics Simulations: The Guiding Role of Aromatic ResiduesModeling and dynamics of the inward-facing state of a Na+/Cl- dependent neurotransmitter transporter homologueSubstrate specificity and ion coupling in the Na+/betaine symporter BetPMolecular basis of substrate-induced permeation by an amino acid antiporterStructures of a Na+-coupled, substrate-bound MATE multidrug transporterArginine oscillation explains Na+ independence in the substrate/product antiporter CaiTMolecular mechanism of ligand recognition by membrane transport protein, Mhp1A gate-free pathway for substrate release from the inward-facing state of the Na⁺-galactose transporterA mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters.Unbiased simulations reveal the inward-facing conformation of the human serotonin transporter and Na(+) ion release.The transport mechanism of the human sodium/myo-inositol transporter 2 (SMIT2/SGLT6), a member of the LeuT structural family.Cytoplasmic permeation pathway of neurotransmitter transporters.Using Haloarcula marismortui bacteriorhodopsin as a fusion tag for enhancing and visible expression of integral membrane proteins in Escherichia coli.Identification of a second substrate-binding site in solute-sodium symporters.Protonation of glutamate 208 induces the release of agmatine in an outward-facing conformation of an arginine/agmatine antiporterA conformational switch in a partially unwound helix selectively determines the pathway for substrate release from the carnitine/γ-butyrobetaine antiporter CaiTCarnitine in bacterial physiology and metabolism.Investigation of the sodium-binding sites in the sodium-coupled betaine transporter BetP.Bacterial stimulus perception and signal transduction: response to osmotic stress.Structural perspectives on secondary active transporters.Substrate and drug binding sites in LeuT.OCTN cation transporters in health and disease: role as drug targets and assay development.The chemical biology of dimethylsulfoniopropionate.The sodium/multivitamin transporter: a multipotent system with therapeutic implications.A comparative study of structures and structural transitions of secondary transporters with the LeuT fold.Alternating access mechanisms of LeuT-fold transporters: trailblazing towards the promised energy landscapes.The alternating access mechanism of transport as observed in the sodium-hydantoin transporter Mhp1.Benchmarking membrane protein detergent stability for improving throughput of high-resolution X-ray structures.Resculpting the binding pocket of APC superfamily LeuT-fold amino acid transporters.
P2860
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P2860
Crystal structure of the carnitine transporter and insights into the antiport mechanism
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Crystal structure of the carnitine transporter and insights into the antiport mechanism
@ast
Crystal structure of the carnitine transporter and insights into the antiport mechanism
@en
Crystal structure of the carnitine transporter and insights into the antiport mechanism
@nl
type
label
Crystal structure of the carnitine transporter and insights into the antiport mechanism
@ast
Crystal structure of the carnitine transporter and insights into the antiport mechanism
@en
Crystal structure of the carnitine transporter and insights into the antiport mechanism
@nl
prefLabel
Crystal structure of the carnitine transporter and insights into the antiport mechanism
@ast
Crystal structure of the carnitine transporter and insights into the antiport mechanism
@en
Crystal structure of the carnitine transporter and insights into the antiport mechanism
@nl
P2093
P2860
P921
P3181
P356
P1476
Crystal structure of the carnitine transporter and insights into the antiport mechanism
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/NSMB.1788
P50
P577
2010-03-28T00:00:00Z
P5875
P6179
1036890247