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Structural basis for the suppression of skin cancers by DNA polymerase η

Structural basis for the suppression of skin cancers by DNA polymerase η

http://www.wikidata.org/entity/Q27662723

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A rescue act: Translesion DNA synthesis past N(2) -deoxyguanosine adducts Structural Basis for Error-free Replication of Oxidatively Damaged DNA by Yeast DNA Polymerase η Mechanism of replication blocking and bypass of Y-family polymerase by bulky acetylaminofluorene DNA adducts Role of Human DNA Polymerase κ in Extension Opposite from a cis–syn Thymine Dimer Implications for Damage Recognition during Dpo4-Mediated Mutagenic Bypass of m1G and m3C Lesions Bypass of Aflatoxin B 1 Adducts by the Sulfolobus solfataricus DNA Polymerase IV Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA Polymerases Y-Family Polymerase Conformation Is a Major Determinant of Fidelity and Translesion Specificity Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase Human DNA Polymerase η Is Pre-Aligned for dNTP Binding and Catalysis A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli Mechanism for priming DNA synthesis by yeast DNA Polymerase α Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin.Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation.Structural Mechanism of Replication Stalling on a Bulky Amino-Polycyclic Aromatic Hydrocarbon DNA Adduct by a Y Family DNA Polymerase The PAD region in the mycobacterial DinB homologue MsPolIV exhibits positional heterogeneity Importance of Polη for damage-induced cohesion reveals differential regulation of cohesion establishment at the break site and genome-wide Evolution of replicative DNA polymerases in archaea and their contributions to the eukaryotic replication machinery An active site aromatic triad in Escherichia coli DNA Pol IV coordinates cell survival and mutagenesis in different DNA damaging agents An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling.Identification of two functional PCNA-binding domains in human DNA polymerase κ Mutation of the little finger domain in human DNA polymerase η alters fidelity when copying undamaged DNA Use of chromophoric ligands to visually screen co-crystals of putative protein-nucleic acid complexes.Error-free replicative bypass of thymine glycol by the combined action of DNA polymerases kappa and zeta in human cells.Selective modulation of DNA polymerase activity by fixed-conformation nucleoside analogues.Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest.Mutator phenotypes due to DNA replication infidelity.DNA polymerases provide a canon of strategies for translesion synthesis past oxidatively generated lesions.Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites Conformational dynamics of a Y-family DNA polymerase during substrate binding and catalysis as revealed by interdomain Förster resonance energy transfer.Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases.Dynamic conformational change regulates the protein-DNA recognition: an investigation on binding of a Y-family polymerase to its target DNA.Surviving the sun: repair and bypass of DNA UV lesions.Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine.Noncognate DNA damage prevents the formation of the active conformation of the Y-family DNA polymerases DinB and DNA polymerase κ MsDpo4-a DinB Homolog from Mycobacterium smegmatis-Is an Error-Prone DNA Polymerase That Can Promote G:T and T:G Mismatches.Molecular mechanisms of xeroderma pigmentosum (XP) proteins.

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Structural basis for the suppression of skin cancers by DNA polymerase η

http://www.wikidata.org/entity/Q27662723

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2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Structural basis for the suppression of skin cancers by DNA polymerase η

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Structural basis for the suppression of skin cancers by DNA polymerase η

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Structural basis for the suppression of skin cancers by DNA polymerase η

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type

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Structural basis for the suppression of skin cancers by DNA polymerase η

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Structural basis for the suppression of skin cancers by DNA polymerase η

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Structural basis for the suppression of skin cancers by DNA polymerase η

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Structural basis for the suppression of skin cancers by DNA polymerase η

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Structural basis for the suppression of skin cancers by DNA polymerase η

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Structural basis for the suppression of skin cancers by DNA polymerase η

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Structural basis for the suppression of skin cancers by DNA polymerase η

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Aneel K Aggarwal

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Rinku Jain

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Robert E Johnson

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Satya Prakash

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Timothy D Silverstein

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P2860

hRAD30 mutations in the variant form of xeroderma pigmentosum

Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Structure of the catalytic core of S. cerevisiae DNA polymerase eta: implications for translesion DNA synthesis

Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a classic polymerase catalytic domain

Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication

Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

Coot: model-building tools for molecular graphics

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