Novel insights into K+ selectivity from high-resolution structures of an open K+ channel pore
about
Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channelCrystal structure of the human two-pore domain potassium channel K2P1Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channelTuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sitesIon concentration-dependent ion conduction mechanism of a voltage-sensitive potassium channelIon Concentration- and Voltage-Dependent Push and Pull Mechanisms of Potassium Channel Ion ConductionMechanism for selectivity-inactivation coupling in KcsA potassium channelsCrucial Points within the Pore as Determinants of K+ Channel Conductance and GatingThe crystal structure of a voltage-gated sodium channelProtein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeationThe voltage-dependent gate in MthK potassium channels is located at the selectivity filterCrystal structure of a heterotetrameric NMDA receptor ion channelIonic interactions of Ba 2+ blockades in the MthK K + channelDeterminants of cation transport selectivity: Equilibrium binding and transport kineticsFast assessment of structural models of ion channels based on their predicted current-voltage characteristics.Structural correlates of selectivity and inactivation in potassium channels.The open gate structure of the membrane-embedded KcsA potassium channel viewed from the cytoplasmic sideInitial steps of inactivation at the K+ channel selectivity filterThe conserved potassium channel filter can have distinct ion binding profiles: structural analysis of rubidium, cesium, and barium binding in NaK2KGeneral rules for the arrangements and gating motions of pore-lining helices in homomeric ion channels.Potassium-selective block of barium permeation through single KcsA channelsVoltage-dependent inactivation gating at the selectivity filter of the MthK K+ channelStructural studies of ion selectivity in tetrameric cation channels.Ion selectivity in channels and transportersOn the selective ion binding hypothesis for potassium channelsAltered and dynamic ion selectivity of K+ channels in cell development and excitabilityCalcium ions open a selectivity filter gate during activation of the MthK potassium channelIBiSA_Tools: A Computational Toolkit for Ion-Binding State Analysis in Molecular Dynamics Trajectories of Ion Channels.Ion-binding properties of a K+ channel selectivity filter in different conformations.Role of protein dynamics in ion selectivity and allosteric coupling in the NaK channel.Nonselective conduction in a mutated NaK channel with three cation-binding sitesICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels.New potential binding determinant for hERG channel inhibitors.Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channelSemisynthetic K+ channels show that the constricted conformation of the selectivity filter is not the C-type inactivated state.Molecular dynamics simulations of scorpion toxin recognition by the Ca(2+)-activated potassium channel KCa3.1.Structural and functional characterization of a calcium-activated cation channel from Tsukamurella paurometabola.Sodium and potassium competition in potassium-selective and non-selective channels.Voltage-gated sodium channels: biophysics, pharmacology, and related channelopathies.K(+) and Na(+) conduction in selective and nonselective ion channels via molecular dynamics simulations
P2860
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P2860
Novel insights into K+ selectivity from high-resolution structures of an open K+ channel pore
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Novel insights into K+ selecti ...... res of an open K+ channel pore
@ast
Novel insights into K+ selecti ...... res of an open K+ channel pore
@en
Novel insights into K+ selecti ...... res of an open K+ channel pore
@nl
type
label
Novel insights into K+ selecti ...... res of an open K+ channel pore
@ast
Novel insights into K+ selecti ...... res of an open K+ channel pore
@en
Novel insights into K+ selecti ...... res of an open K+ channel pore
@nl
prefLabel
Novel insights into K+ selecti ...... res of an open K+ channel pore
@ast
Novel insights into K+ selecti ...... res of an open K+ channel pore
@en
Novel insights into K+ selecti ...... res of an open K+ channel pore
@nl
P2093
P2860
P3181
P356
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Novel insights into K+ selecti ...... res of an open K+ channel pore
@en
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10.1038/NSMB.1865
P577
2010-08-01T00:00:00Z
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1015558161