The crystal structure of a constitutively active mutant RON kinase suggests an intramolecular autophosphorylation hypothesis
about
Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addictionAssessing the range of kinase autoinhibition mechanisms in the insulin receptor familyIdentifying three-dimensional structures of autophosphorylation complexes in crystals of protein kinasesIntron retention in the alternatively spliced region of RON results from weak 3' splice site recognition.Mutations in RIPK4 cause the autosomal-recessive form of popliteal pterygium syndrome.Strategies of targeting the extracellular domain of RON tyrosine kinase receptor for cancer therapy and drug delivery.Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain.The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase.MST1R autophosphorylates
P2860
Q26864275-EFAFDE6A-D46A-4BFD-B8D7-AEEFE94E30AAQ27673414-ADC86B56-2883-41FC-A624-5F430EA03012Q28270556-7F8F3AA5-6BC0-4020-BC7B-1BE7934831BCQ35025393-DC42E7EE-86D5-4A10-A94F-70A40CFA8D63Q35671532-FB6DE74F-55BE-4BF2-A915-A4CEA1C130FEQ38922319-28447C30-1A47-4837-8A22-589EC9F9A16BQ39628474-56D71A35-352B-46C3-B262-1AF5D233F9EBQ46659031-486349D8-CB97-4237-8AB9-25C5F0848434Q50298150-7B5D3D96-900C-49B5-94FE-AFF48B0680F3
P2860
The crystal structure of a constitutively active mutant RON kinase suggests an intramolecular autophosphorylation hypothesis
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The crystal structure of a con ...... autophosphorylation hypothesis
@ast
The crystal structure of a con ...... autophosphorylation hypothesis
@en
The crystal structure of a con ...... autophosphorylation hypothesis
@nl
type
label
The crystal structure of a con ...... autophosphorylation hypothesis
@ast
The crystal structure of a con ...... autophosphorylation hypothesis
@en
The crystal structure of a con ...... autophosphorylation hypothesis
@nl
prefLabel
The crystal structure of a con ...... autophosphorylation hypothesis
@ast
The crystal structure of a con ...... autophosphorylation hypothesis
@en
The crystal structure of a con ...... autophosphorylation hypothesis
@nl
P2093
P356
P1433
P1476
The crystal structure of a con ...... utophosphorylation hypothesis.
@en
P2093
Andrew P Crew
David Epstein
Mark J Mulvihill
Martin Augustin
Patrick Schreiner
P304
P356
10.1021/BI100409W
P407
P577
2010-09-21T00:00:00Z