A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity - Wikidata - wikimedia - TriplyDB

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

http://www.wikidata.org/entity/Q27664589

about

Electrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomics Recent strategies targeting HIV glycans in vaccine design Designing synthetic vaccines for HIV Glycotherapy: new advances inspire a reemergence of glycans in medicine Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization Water molecules inside protein structure affect binding of monosaccharides with HIV-1 antibody 2G12.Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infection Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates Synthetic carbohydrate antigens for HIV vaccine design.The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.Antibody recognition of fluorinated MUC1 glycopeptide antigens.Antibody evasion by a gammaherpesvirus O-glycan shield AIDS/HIV. Host controls of HIV neutralizing antibodies.Creation of an α-mannosynthase from a broad glycosidase scaffold.Chemo-enzymatic synthesis and in vitro cytokine profiling of tailor-made oligofructosides.Prime-boost immunization of rabbits with HIV-1 gp120 elicits potent neutralization activity against a primary viral isolate.Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose Directed evolution of multivalent glycopeptides tightly recognized by HIV antibody 2G12.High-mannose glycan-dependent epitopes are frequently targeted in broad neutralizing antibody responses during human immunodeficiency virus type 1 infection.Antigenicity and Immunogenicity in HIV-1 Antibody-Based Vaccine Design 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies.Development of prophylactic vaccines against HIV-1.Glycomaterials for probing host-pathogen interactions and the immune response.Carbohydrate chemistry in drug discovery.Toward automated oligosaccharide synthesis.Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA.Design and synthesis of a "click" high-mannose oligosaccharide mimic emulating Man8 binding affinity towards Con A.Recent Developments in Synthetic Carbohydrate-Based Diagnostics, Vaccines, and Therapeutics.Broadly Neutralizing Antibody-Guided Carbohydrate-Based HIV Vaccine Design: Challenges and Opportunities.High temperature SELMA: evolution of DNA-supported oligomannose clusters which are tightly recognized by HIV bnAb 2G12.A cancer vaccine based on fluorine-modified sialyl-Tn induces robust immune responses in a murine model.Electrochemical lectin based biosensors as a label-free tool in glycomics.Synthetically defined glycoprotein vaccines: current status and future directions.Ready access to a branched Man5 oligosaccharide based on regioselective glycosylations of a mannose-tetraol with n-pentenyl orthoesters.Directed evolution of 2G12-targeted nonamannose glycoclusters by SELMA.Ultrasensitive impedimetric lectin biosensors with efficient antifouling properties applied in glycoprofiling of human serum samples.Sequence-controlled multi-block glycopolymers to inhibit DC-SIGN-gp120 binding.

P2860

Q26822552-56DC022E-C56F-49A6-957A-C1227F335BBA Q26823603-7976582C-EFE2-4429-B5DE-322769B7CE29 Q26862617-95F237D9-E468-41AE-9D84-02B9D4D51F03 Q27027997-AA60E166-7B5E-4C0B-BC4E-AC168F7660E7 Q27684578-DA30BCC4-3138-4F9C-953D-88EF8D1E7087 Q30390267-7C0E7430-9580-4F22-8CB9-E8BE1FC74001 Q30531089-6FB7ED45-05B6-45EB-94DE-0B279E99920B Q33612459-42DE181A-B9BC-49A3-AEB8-6B16E8F7AA0C Q33909079-5E249465-C483-4320-9436-E8ADF17CDB43 Q33999756-B59AC6B7-BF2F-4A3E-A62E-B5513EC3090C Q34045866-C3557FA3-D189-4742-A93D-53AB94BFA560 Q34082672-EBBF4922-E75C-47FB-A4E2-96D3D74722AC Q34170264-7F9CADE9-218A-4933-B491-A54419E989E2 Q34281309-1387BD2B-D38F-463C-A508-F0139D718E30 Q34488461-C4827408-F19D-4510-A2A2-99689D8BE653 Q34551010-B2F0D808-433C-4D74-8461-50253E42381C Q35119778-004587E9-D6FF-4429-9156-31CF56955335 Q35124652-0FF76B41-6A2E-4416-9835-F451F322CC82 Q35826509-5AB8F69D-6D0F-43B5-B46A-732FD5CE8715 Q36447540-3E0BE051-8D71-4392-A996-6090F12C0299 Q36607316-D3AEB064-C1AD-4BCC-8DC4-4390F245EB58 Q37042563-6B77808B-F4A8-40BA-9A58-05852FD895DC Q37107154-D197D6A2-437C-4D68-A475-5D7E00975895 Q37853437-372F3065-3A7E-4783-9405-CE736717C77F Q37962848-5E528015-48E0-44E0-89AD-6451D89F2352 Q38050485-127233E3-70D8-426F-B464-EF00ADF3CAB4 Q38327086-A9BB2BAF-3D44-4849-AD2F-C093BA0EBF3E Q38533442-E080685F-88ED-4359-A24E-B82E96CDC521 Q38695294-12E5874C-64B4-48B1-93A8-E835C26DDECC Q38732360-BB4F9F37-6A0F-4F80-97EF-8561198F374B Q38767397-53AC39B3-D713-4332-8CB9-7CF75B1CDB34 Q38847934-B6A2D162-CDD4-4F8F-BA42-A81591A62E6E Q39375701-8C2D0C7C-BC72-4EC6-8882-6B02F1978FE6 Q39548749-0522239C-906D-47AC-A800-E9421B78A89E Q41879689-2EEE2786-B0A8-4808-8B5A-253F30A94EA4 Q42571075-8D5DB5A6-6545-48FC-958C-332DDEF578A2 Q44555796-D14F7BDB-6E04-4EC1-8847-48F5B131C47B

P2860

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

http://www.wikidata.org/entity/Q27664589

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

@ast

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

@en

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

@nl

type

label

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

@ast

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

@en

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

@nl

prefLabel

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

@ast

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

@en

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

@nl

P1433

Q27664589-33E2FF5F-1EF1-42FC-A9D7-CDDDC01B6A4E

P1476

Q27664589-F8410D72-63FB-408C-AED0-328E7298932A

P2093

Q27664589-1C757545-7AB9-4A89-B947-F83A7B7D7B62

Q27664589-BC1ED55E-D289-41E5-BD0D-0C9856694BB5

Q27664589-C26DAF8D-FCE0-426C-AE31-1C39FC9B72FB

Q27664589-EEB0FC7C-1290-45C0-B774-FE4EE226227B

Q27664589-F707B356-5E89-4944-BACD-1ADE41334B0D

Q27664589-F7AC193C-3AE0-47AC-96F4-88B85EFFD3B1

P2860

Q27664589-0659B666-7204-4AD5-B197-780854263B1A

Q27664589-07496816-75E3-4191-B258-F7856C8A0CCA

Q27664589-1E0516A2-92C7-47EC-82D1-C14847C28DE5

Q27664589-2816488C-95AB-4B47-AE2D-7487ECC58F54

Q27664589-28F3BEBE-FED8-4305-AEF7-B2E2B391EA0B

Q27664589-2B39B507-99C6-4003-900E-EF59769CEDD5

Q27664589-2CB4E00A-FBEE-4CAD-A8FF-69AE057DAF01

Q27664589-31DAE830-9167-4A31-97B0-7090A3C1F3DC

Q27664589-3455DBC9-30D7-466F-9632-4849B1AB15B7

Q27664589-452BD99A-6A46-43E6-A2B9-A3BCF7BBB355

P304

Q27664589-789924A6-50F7-472A-AEB5-B612A8D85BA5

P31

Q27664589-F61DB13C-6358-469E-967A-9C564EA4ED04

P356

Q27664589-41B43EA4-10B1-4D7E-969B-586DA6EA9102

P407

Q27664589-B758B186-C982-4DA2-9EA2-F69ACE15B51B

P433

Q27664589-B4438234-FBDD-4517-98EF-2D05468DACC3

P478

Q27664589-AADBD04F-B801-41E4-9421-143E1F0D5C33

P50

Q27664589-17C2209C-04CE-45EA-B5B8-FE004699A356

Q27664589-419341E7-247F-4D19-BD41-CBD918F04A9C

Q27664589-4F15CBA3-3315-4854-97BF-2CB8751F9312

Q27664589-A6C56F4B-DB1D-4139-895E-58F19B060527

P577

Q27664589-F1ADEEE3-D3FC-4095-A91A-F17EEBD13644

P5875

Q27664589-7AF9DEAE-4007-4BB6-A7AC-565D860F1A18

P698

Q27664589-2A34D205-D53F-4BA9-B82C-2987A4F3CC72

P921

Q27664589-7BB68160-2DD7-4924-8892-2AE721ABB966

Q27664589-B9E230CA-1A4F-49B7-B31F-53A355AEB108

Q27664589-C5F5CC8F-CA4B-470A-A229-D7BA3B6C846C

P932

Q27664589-638D39C3-45C0-4B19-958A-3ECDB39AFDE7

P356

PNAS.1002717107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

@en

P2093

Benjamin G Davis

http://www.w3.org/2001/XMLSchema#string

Christopher N Scanlan

http://www.w3.org/2001/XMLSchema#string

Dennis R Burton

http://www.w3.org/2001/XMLSchema#string

Mitul K Patel

http://www.w3.org/2001/XMLSchema#string

Vu Hong

http://www.w3.org/2001/XMLSchema#string

Zara Fulton

http://www.w3.org/2001/XMLSchema#string

P2860

Structural definition of a conserved neutralization epitope on HIV-1 gp120

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing Antibodies

Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41

The antigenic structure of the HIV gp120 envelope glycoprotein

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN

P304

17107-12

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1002717107

http://www.w3.org/2001/XMLSchema#string

P407

P433

40

http://www.w3.org/2001/XMLSchema#string

P478

107

http://www.w3.org/2001/XMLSchema#string

P50

Ian Andrew Wilson

P577

2010-10-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

46306288

http://www.w3.org/2001/XMLSchema#string

P698

20852065

http://www.w3.org/2001/XMLSchema#string

P921

(6S)-6-C-methyl-D-mannopyranose

6-C-Me-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->3)-alpha-D-Manp

beta-D-fructopyranose

P932

2951454

http://www.w3.org/2001/XMLSchema#string