A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation
about
A Nod to disease vectors: mitigation of pathogen sensing by arthropod salivaTryptogalinin is a tick Kunitz serine protease inhibitor with a unique intrinsic disorderIn Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplusA further insight into the sialome of the tropical bont tick, Amblyomma variegatumPlasmodium falciparum infection induces expression of a mosquito salivary protein (Agaphelin) that targets neutrophil function and inhibits thrombosis without impairing hemostasisUnderstanding the evolutionary structural variability and target specificity of tick salivary Kunitz peptides using next generation transcriptome data.The tick salivary protein sialostatin L2 inhibits caspase-1-mediated inflammation during Anaplasma phagocytophilum infection.Serine Protease Inhibitors in Ticks: An Overview of Their Role in Tick Biology and Tick-Borne Pathogen Transmission.Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction.Deorphanization and target validation of cross-tick species conserved novel Amblyomma americanum tick saliva protein.Amblyomma americanum tick saliva serine protease inhibitor 6 is a cross-class inhibitor of serine proteases and papain-like cysteine proteases that delays plasma clotting and inhibits platelet aggregationA blood meal-induced Ixodes scapularis tick saliva serpin inhibits trypsin and thrombin, and interferes with platelet aggregation and blood clotting.A 24-48 h fed Amblyomma americanum tick saliva immuno-proteome.Immunity-related genes in Ixodes scapularis--perspectives from genome informationA deep insight into the sialotranscriptome of the gulf coast tick, Amblyomma maculatumSimukunin from the salivary glands of the black fly Simulium vittatum inhibits enzymes that regulate clotting and inflammatory responses.Vaccination against Lyme disease: past, present, and futureMidgut expression of immune-related genes in Glossina palpalis gambiensis challenged with Trypanosoma brucei gambiense.Bioinformatic analyses of male and female Amblyomma americanum tick expressed serine protease inhibitors (serpins).The sialotranscriptome of Amblyomma triste, Amblyomma parvum and Amblyomma cajennense ticks, uncovered by 454-based RNA-seq.A serpin released by an entomopathogen impairs clot formation in insect defense systemRhipicephalus microplus serine protease inhibitor family: annotation, expression and functional characterisation assessment.Sexual differences in the sialomes of the zebra tick, Rhipicephalus pulchellus.Finding off-targets, biological pathways, and target diseases for chymase inhibitors via structure-based systems biology approach.Ixodes ricinus salivary serpin IRS-2 affects Th17 differentiation via inhibition of the interleukin-6/STAT-3 signaling pathwayDeep Sequencing Analysis of the Ixodes ricinus Haemocytome.Saliva from nymph and adult females of Haemaphysalis longicornis: a proteomic studyConserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions.Ixodes scapularis Tick Saliva Proteins Sequentially Secreted Every 24 h during Blood Feeding.Tick salivary secretion as a source of antihemostatics.The Anopheles gambiae cE5, a tight- and fast-binding thrombin inhibitor with post-transcriptionally regulated salivary-restricted expressionModulation of host immunity by tick saliva.The roles of serpins in mosquito immunology and physiologySialomes and Mialomes: A Systems-Biology View of Tick Tissues and Tick-Host Interactions.The putative role of Rhipicephalus microplus salivary serpins in the tick-host relationshipPartial characterization of a novel anti-inflammatory protein from salivary gland extract of Hyalomma anatolicum anatolicum 77Acari: Ixodidae) ticks.Characterization of Ixophilin, a thrombin inhibitor from the gut of Ixodes scapularisTick salivary compounds: their role in modulation of host defences and pathogen transmissionDe novo Ixodes ricinus salivary gland transcriptome analysis using two next-generation sequencing methodologies.Pnserpin: A Novel Serine Protease Inhibitor from Extremophile Pyrobaculum neutrophilum
P2860
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P2860
A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation
description
2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
A tick salivary protein target ...... ation and platelet aggregation
@ast
A tick salivary protein target ...... ation and platelet aggregation
@en
A tick salivary protein target ...... ation and platelet aggregation
@nl
type
label
A tick salivary protein target ...... ation and platelet aggregation
@ast
A tick salivary protein target ...... ation and platelet aggregation
@en
A tick salivary protein target ...... ation and platelet aggregation
@nl
prefLabel
A tick salivary protein target ...... ation and platelet aggregation
@ast
A tick salivary protein target ...... ation and platelet aggregation
@en
A tick salivary protein target ...... ation and platelet aggregation
@nl
P2093
P2860
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P1433
P1476
A tick salivary protein target ...... ation and platelet aggregation
@en
P2093
Carlo J Oliveira
Gunnar Pejler
Ivo M B Francischetti
Jan Kopecky
Michael Mares
Michail Kotsyfakis
Peter Kopacek
Zuzana Kovarova
P2860
P304
P356
10.1182/BLOOD-2010-06-293241
P407
P577
2010-10-12T00:00:00Z