FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
about
Pharmacology and Clinical Drug Candidates in Redox MedicineMechanistic insights into xanthine oxidoreductase from development studies of candidate drugs to treat hyperuricemia and goutMechanism of porcine liver xanthine oxidoreductase mediated N-oxide reduction of cyadox as revealed by docking and mutagenesis studiesThe mononuclear molybdenum enzymes.Effects of topiroxostat on the serum urate levels and urinary albumin excretion in hyperuricemic stage 3 chronic kidney disease patients with or without goutHyperuricemia-Related Diseases and Xanthine Oxidoreductase (XOR) Inhibitors: An Overview.Identification of Febuxostat as a New Strong ABCG2 Inhibitor: Potential Applications and Risks in Clinical Situations.Clinical Effects of Topiroxostat on Renal and Endothelial Function in A Patient with Chronic Kidney Disease and Hyperuricemic Arteriolopathy: A Case Report.Clinical efficacy and safety of topiroxostat in Japanese hyperuricemic patients with or without gout: a randomized, double-blinded, controlled phase 2b study.Xanthine oxidase inhibitors: a patent survey.Chemical nature and reaction mechanisms of the molybdenum cofactor of xanthine oxidoreductaseToward an Understanding of Structural Insights of Xanthine and Aldehyde Oxidases: An Overview of their Inhibitors and Role in Various Diseases.Significant reduction in errors associated with nonbonded contacts in protein crystal structures: automated all-atom refinement with PrimeX.Uricosuric agents decrease the plasma urate level in rats by concomitant treatment with topiroxostat, a novel xanthine oxidoreductase inhibitor.Enhancement of pharmacological effects of uricosuric agents by concomitant treatment with pyrazinamide in rats.Design, synthesis, and molecular docking studies of N-(9,10-anthraquinone-2-carbonyl)amino acid derivatives as xanthine oxidase inhibitors.Design, synthesis, and biological evaluation of 5-(4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)benzonitrile derivatives as xanthine oxidase inhibitors.Physiology of Hyperuricemia and Urate-Lowering Treatments.
P2860
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P2860
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
@ast
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
@en
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
@nl
type
label
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
@ast
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
@en
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
@nl
prefLabel
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
@ast
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
@en
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
@nl
P2093
P3181
P356
P1476
FYX-051: a novel and potent hybrid-type inhibitor of xanthine oxidoreductase
@en
P2093
Ken Okamoto
Koji Matsumoto
Naoki Ashizawa
Takeshi Nishino
P304
P3181
P356
10.1124/JPET.110.174540
P407
P577
2011-01-01T00:00:00Z