The mechanism of retroviral integration from X-ray structures of its key intermediates
about
Multifunctional facets of retrovirus integraseYeast and the AIDS virus: the odd coupleEvolution of foamy viruses: the most ancient of all retrovirusesFoamy virus assembly with emphasis on pol encapsidationFoamy virus biology and its application for vector developmentBlind prediction of HIV integrase binding from the SAMPL4 challengeNovel therapeutic strategies targeting HIV integraseCrystal structure of the Rous sarcoma virus intasome.Retroviral intasomes search for a target DNA by 1D diffusion which rarely results in integrationDNA minicircles clarify the specific role of DNA structure on retroviral integrationMolecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance.Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572)A Crystal Structure of the Catalytic Core Domain of an Avian Sarcoma and Leukemia Virus Integrase Suggests an Alternate Dimeric AssemblyAssembly of prototype foamy virus strand transfer complexes on product DNA bypassing catalysis of integrationActivities, Crystal Structures, and Molecular Dynamics of Dihydro-1 H -isoindole Derivatives, Inhibitors of HIV-1 IntegraseThe Mu transpososome structure sheds light on DDE recombinase evolutionAn Enzyme-Catalyzed Multistep DNA Refolding Mechanism in Hairpin Telomere FormationA possible role for the asymmetric C-terminal domain dimer of Rous sarcoma virus integrase in viral DNA binding3′-Processing and strand transfer catalysed by retroviral integrasein crystalloStructural Basis of hAT Transposon End Recognition by Hermes, an Octameric DNA Transposase from Musca domesticaA bend, flip and trap mechanism for transposon integrationThe Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally CriticalRetroviral Integrase: Then and NowRetroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selectionLocalization of ASV integrase-DNA contacts by site-directed crosslinking and their structural analysisStructure-analysis of the HIV-1 integrase Y143C/R raltegravir resistance mutation in association with the secondary mutation T97ABF integrase genes of HIV-1 circulating in São Paulo, Brazil, with a recurrent recombination regionBiochemical characterization of novel retroviral integrase proteinsEngineered hyperactive integrase for concerted HIV-1 DNA integrationStructural Studies of the HIV-1 Integrase Protein: Compound Screening and Characterization of a DNA-Binding InhibitorRetroviral DNA IntegrationIntegration profiling of gene function with dense maps of transposon integrationHsmar1 transposition is sensitive to the topology of the transposon donor and the targetThe RNase H-like superfamily: new members, comparative structural analysis and evolutionary classification.Structural and sequencing analysis of local target DNA recognition by MLV integrase.Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integrationArchitecture of a full-length retroviral integrase monomer and dimer, revealed by small angle X-ray scattering and chemical cross-linkingStructural and functional role of INI1 and LEDGF in the HIV-1 preintegration complex.Solution conformations of prototype foamy virus integrase and its stable synaptic complex with U5 viral DNA.Predicting protein-DNA interactions by full search computational docking.
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P2860
The mechanism of retroviral integration from X-ray structures of its key intermediates
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The mechanism of retroviral integration from X-ray structures of its key intermediates
@ast
The mechanism of retroviral integration from X-ray structures of its key intermediates
@en
The mechanism of retroviral integration from X-ray structures of its key intermediates
@nl
type
label
The mechanism of retroviral integration from X-ray structures of its key intermediates
@ast
The mechanism of retroviral integration from X-ray structures of its key intermediates
@en
The mechanism of retroviral integration from X-ray structures of its key intermediates
@nl
prefLabel
The mechanism of retroviral integration from X-ray structures of its key intermediates
@ast
The mechanism of retroviral integration from X-ray structures of its key intermediates
@en
The mechanism of retroviral integration from X-ray structures of its key intermediates
@nl
P2860
P50
P3181
P356
P1433
P1476
The mechanism of retroviral integration from X-ray structures of its key intermediates
@en
P2860
P2888
P3181
P356
10.1038/NATURE09517
P407
P577
2010-11-11T00:00:00Z
P5875
P6179
1004415428