Active mutants of the TCR-mediated p38α alternative activation site show changes in the phosphorylation lip and DEF site formation
about
Crystal structure of the p38α MAP kinase in complex with a docking peptide from TAB1Co-conserved MAPK features couple D-domain docking groove to distal allosteric sites via the C-terminal flanking tailNMR Characterization of Information Flow and Allosteric Communities in the MAP Kinase p38γTighter αC-helix-αL16-helix interactions seem to make p38α less prone to activation by autophosphorylation than Hog1.DEF pocket in p38α facilitates substrate selectivity and mediates autophosphorylation.Synthetic phosphorylation of p38α recapitulates protein kinase activityConformational bias imposed by source microseeds results in structural ambiguity.A Comprehensive Structural Overview of p38α Mitogen-Activated Protein Kinase in Complex with ATP-Site and Non-ATP-Site Binders.Mechanism of dual specificity kinase activity of DYRK1A.
P2860
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P2860
Active mutants of the TCR-mediated p38α alternative activation site show changes in the phosphorylation lip and DEF site formation
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Active mutants of the TCR-medi ...... ion lip and DEF site formation
@ast
Active mutants of the TCR-medi ...... ion lip and DEF site formation
@en
Active mutants of the TCR-medi ...... ion lip and DEF site formation
@nl
type
label
Active mutants of the TCR-medi ...... ion lip and DEF site formation
@ast
Active mutants of the TCR-medi ...... ion lip and DEF site formation
@en
Active mutants of the TCR-medi ...... ion lip and DEF site formation
@nl
prefLabel
Active mutants of the TCR-medi ...... ion lip and DEF site formation
@ast
Active mutants of the TCR-medi ...... ion lip and DEF site formation
@en
Active mutants of the TCR-medi ...... ion lip and DEF site formation
@nl
P2093
P3181
P1476
Active mutants of the TCR-medi ...... ion lip and DEF site formation
@en
P2093
David Engelberg
Oded Livnah
Ron Diskin
P304
P3181
P356
10.1016/J.JMB.2010.11.023
P407
P577
2010-12-10T00:00:00Z