Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis

Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis

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http://www.wikidata.org/entity/Q27666494
Replisome Assembly at Bacterial Chromosomes and Iteron PlasmidsM. tuberculosis Sliding β-Clamp Does Not Interact Directly with the NAD+ -Dependent DNA LigaseAntibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycinsCrystal structure of the DNA polymerase III β subunit (β-clamp) from the extremophile Deinococcus radiodurans.New Structural Templates for Clinically Validated and Novel Targets in Antimicrobial Drug Research and Development.The β2 clamp in the Mycobacterium tuberculosis DNA polymerase III αβ2ε replicase promotes polymerization and reduces exonuclease activity.Maximum flow approach to prioritize potential drug targets of Mycobacterium tuberculosis H37Rv from protein-protein interaction networkRepurposing drugs for treatment of tuberculosis: a role for non-steroidal anti-inflammatory drugs.An Approach for Identification of Novel Drug Targets in Streptococcus pyogenes SF370 Through Pathway Analysis.High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center.Sliding Clamp of DNA Polymerase III as a Drug Target for TB Therapy: Comprehensive Conformational and Binding Analysis from Molecular Dynamic Simulations.Rv0004 is a new essential member of the mycobacterial DNA replication machinery.Tricyclic dihydrobenzoxazepine and tetracyclic indole derivatives can specifically target bacterial DNA ligases and can distinguish them from human DNA ligase I.Mycobacterium tuberculosis class II apurinic/apyrimidinic-endonuclease/3'-5' exonuclease III exhibits DNA regulated modes of interaction with the sliding DNA β-clamp.
P2860

Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis

Item
http://www.wikidata.org/entity/Q27666494
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis
@ast
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis
@en
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis
@nl
type
label
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis
@ast
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis
@en
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis
@nl
prefLabel
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis
@ast
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis
@en
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis
@nl
P1433
P1476
P2093
P304
P31
P3181
P356
P407
P433
P478
P577
P5875
P698
P921
P3181
P356
P1433
P1476
Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis
@en
P2093
P304
P31
P3181
P356
10.1016/J.BBRC.2011.01.027
P407
P433
P478
P577
P5875
P698
P921