Crystal structure of the intraflagellar transport complex 25/27
about
The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.Cilia/Ift protein and motor -related bone diseases and mouse modelsPrimary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengersIFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.KIAA0556 is a novel ciliary basal body component mutated in Joubert syndromeThe structure of the cysteine protease and lectin-like domains of Cwp84, a surface layer-associated protein fromClostridium difficileCrystal structure of a Chlamydomonas reinhardtii flagellar RabGAP TBC-domain at 1.8 Å resolutionArchitecture and function of IFT complex proteins in ciliogenesisIntraflagellar transport complex structure and cargo interactions.The roles of evolutionarily conserved functional modules in cilia-related trafficking.IFT-Cargo Interactions and Protein Transport in CiliaIFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndromeIFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transportPrimary cilia are specialized calcium signalling organellesThe eukaryotic flagellum makes the day: novel and unforeseen roles uncovered after post-genomics and proteomics data.Dissecting the sequential assembly and localization of intraflagellar transport particle complex B in Chlamydomonas.Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis.An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuliEvolution of modular intraflagellar transport from a coatomer-like progenitor.Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral SubcomplexThe GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transportStructural studies of ciliary components.Novel topography of the Rab11-effector interaction network within a ciliary membrane targeting complex.Chlamydomonas IFT25 is dispensable for flagellar assembly but required to export the BBSome from flagella.The Intraflagellar Transport Machinery.Microtubule Motors Drive Hedgehog Signaling in Primary Cilia.The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex.A novel bicistronic expression system composed of the intraflagellar transport protein gene ift25 and FMDV 2A sequence directs robust nuclear gene expression in Chlamydomonas reinhardtii.Isolation of intraflagellar transport trains.Biophysical and Structural Characterization of the Centriolar Protein Cep104 Interaction NetworkThe CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.Recombinant Reconstitution and Purification of the IFT-B Core Complex from Chlamydomonas reinhardtii.Biochemical mapping of interactions within the intraflagellar transport (IFT) B core complex: IFT52 binds directly to four other IFT-B subunits.Rab GTPases in cilium formation and function.Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly.IFT25, an intraflagellar transporter protein dispensable for ciliogenesis in somatic cells, is essential for sperm flagella formation.Intraflagellar transporter protein (IFT27), an IFT25 binding partner, is essential for male fertility and spermiogenesis in mice.Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.The RABL5 homolog IFT22 regulates the cellular pool size and the amount of IFT particles partitioned to the flagellar compartment in Chlamydomonas reinhardtii.
P2860
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P2860
Crystal structure of the intraflagellar transport complex 25/27
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Crystal structure of the intraflagellar transport complex 25/27
@ast
Crystal structure of the intraflagellar transport complex 25/27
@en
Crystal structure of the intraflagellar transport complex 25/27
@nl
type
label
Crystal structure of the intraflagellar transport complex 25/27
@ast
Crystal structure of the intraflagellar transport complex 25/27
@en
Crystal structure of the intraflagellar transport complex 25/27
@nl
prefLabel
Crystal structure of the intraflagellar transport complex 25/27
@ast
Crystal structure of the intraflagellar transport complex 25/27
@en
Crystal structure of the intraflagellar transport complex 25/27
@nl
P2860
P50
P356
P1433
P1476
Crystal structure of the intraflagellar transport complex 25/27
@en
P2093
Michaela Morawetz
P2860
P304
P356
10.1038/EMBOJ.2011.110
P407
P577
2011-05-18T00:00:00Z