Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor

Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor

Item
http://www.wikidata.org/entity/Q27667741
Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary DiseasesBioinformatics and variability in drug response: a protein structural perspective.Neutrophil elastase inhibitors: recent advances in the development of mechanism-based and nonelectrophilic inhibitors.Neutrophil elastase inhibitors: a patent review and potential applications for inflammatory lung diseases (2010 - 2014).Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease.A Novel ELANE Mutation Associated with Inflammatory Arthritis, Defective NETosis, and Recurrent Parvoviral Infection.Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions.Asn347 Glycosylation of Corticosteroid-binding Globulin Fine-tunes the Host Immune Response by Modulating Proteolysis by Pseudomonas aeruginosa and Neutrophil Elastase.Role of Proteases in Chronic Obstructive Pulmonary Disease.Quantitative structure-activity relationship analysis of human neutrophil elastase inhibitors using shuffling classification and regression trees and adaptive neuro-fuzzy inference systems.Clickable 4-Oxo-β-lactam-Based Selective Probing for Human Neutrophil Elastase Related Proteomes.
P2860

Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor

Item
http://www.wikidata.org/entity/Q27667741
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Unexpected active-site flexibi ...... ew dihydropyrimidone inhibitor
@ast
Unexpected active-site flexibi ...... ew dihydropyrimidone inhibitor
@en
Unexpected active-site flexibi ...... ew dihydropyrimidone inhibitor
@nl
type
label
Unexpected active-site flexibi ...... ew dihydropyrimidone inhibitor
@ast
Unexpected active-site flexibi ...... ew dihydropyrimidone inhibitor
@en
Unexpected active-site flexibi ...... ew dihydropyrimidone inhibitor
@nl
prefLabel
Unexpected active-site flexibi ...... ew dihydropyrimidone inhibitor
@ast
Unexpected active-site flexibi ...... ew dihydropyrimidone inhibitor
@en
Unexpected active-site flexibi ...... ew dihydropyrimidone inhibitor
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Unexpected active-site flexibi ...... ew dihydropyrimidone inhibitor
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698