Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway - Wikidata - wikimedia - TriplyDB

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

http://www.wikidata.org/entity/Q27670898

about

Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway Direct and Propagated Effects of Small Molecules on Protein-Protein Interaction Networks The Fanconi anemia pathway and DNA interstrand cross-link repair Fanconi anemia pathway defects in inherited and sporadic cancers Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real time Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA.The genetic and biochemical basis of FANCD2 monoubiquitination Interactive cellular proteins related to classical swine fever virus non-structure protein 2 by yeast two-hybrid analysis.The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL FANCL ubiquitinates β-catenin and enhances its nuclear function.Regulation of the Fanconi anemia pathway by a CUE ubiquitin-binding domain in the FANCD2 protein.The Simple Chordate Ciona intestinalis Has a Reduced Complement of Genes Associated with Fanconi Anemia.The PI3K/Akt1 pathway enhances steady-state levels of FANCL.The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2.Stress and DNA repair biology of the Fanconi anemia pathway The Fanconi anemia ID2 complex: dueling saxes at the crossroads.Specificity and disease in the ubiquitin system Towards a molecular understanding of the fanconi anemia core complex Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements.Structural insights into the nanomolar affinity of RING E3 ligase ZNRF1 for Ube2N and its functional implications.

P2860

Q26752319-A24C99AD-D6E2-48EF-A493-85899E591F1B Q26784027-967CAD52-BD4A-4D56-B857-2482CFB1360A Q26851561-A9C221C5-1013-4472-8B86-ACDA2233E9B8 Q26852818-457C74F6-D4A7-4BAA-81A4-AE8FEAC96310 Q27681171-E0B59714-2AA3-4C26-ACD2-20CB1E7287BE Q28067393-2F0E7531-6543-425D-953B-FB6741E98B91 Q28253043-46307C57-D1FA-42B1-B83C-D2B48286B80B Q33635631-E789BCCD-1708-4766-A59A-E9B9FCC9AAA8 Q33735561-303074C0-DE43-43F1-9C82-F9D73B28D455 Q34449988-ECD2B746-810E-4CC0-B82B-484FA81A541D Q34483757-CC304F68-DF5F-4D27-A64A-2B808AAEBE7E Q36100439-2572BE97-9230-4DDB-826F-3908F88F17EC Q36220736-54B8B975-A80D-4620-902A-429E735E37D1 Q36982306-0DB5279A-4F87-4442-8A2C-FFFFB86F86B8 Q37098762-C7CFB5A8-F7F1-4AB4-9352-3438E771BA26 Q37607318-035E4EE5-E541-4122-A15F-9572BA5AD283 Q38252562-A865456F-5214-4B9F-A1F5-0A891F1774CF Q38285213-9A55CAD2-5B7F-446C-A2DC-2051FA8BB112 Q38728113-E5667F6B-EACA-428F-A6AA-F367966AB159 Q42182034-86C88E07-CB7D-4BBB-9BD6-6494D747AE51 Q46144594-73975D3D-1134-4D41-9EFC-EBCF01D7AE4F Q52329489-E16A35C8-9BF7-4369-ACC5-B287925F158D

P2860

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

http://www.wikidata.org/entity/Q27670898

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@ast

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@en

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@en-gb

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@nl

type

label

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@ast

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@en

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@en-gb

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@nl

prefLabel

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@ast

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@en

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@en-gb

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@nl

P1433

Q27670898-1CB56871-2AD5-4F1B-A77C-72ECC5D71896

P1476

Q27670898-B613DE97-D58E-4D5F-BA34-CF381A4FF99C

P2093

Q27670898-1B0A74AA-A106-4563-BD53-4F2F2B064E2B

Q27670898-24AD0275-D9D9-4AA7-8D1E-B19ED47BEB16

Q27670898-69366DAE-749A-43A3-8705-C76DCBC9EE89

Q27670898-8F07C079-9E46-44A1-B444-4A24BA163A06

Q27670898-F71D31E3-FCB6-4B78-BAFE-56EE4BD8CA99

P2860

Q27670898-0B3F33AD-6CF1-44AC-A7F0-D92265593AD7

Q27670898-0E044402-848F-4FB6-8DAB-3671A50A935B

Q27670898-16276403-D4EB-46FF-9F2B-2440F3FCA2E8

Q27670898-1DAD6EFC-D574-4C11-A43D-759187B263F8

Q27670898-1F13C9CB-19BA-425C-B7DC-974778C89175

Q27670898-2378D6FD-DA68-427C-B507-459A47EBF7BC

Q27670898-2768B042-45D9-468B-AD4B-32B8875D2103

Q27670898-314BA31A-821E-4CFD-B305-126B277B71A5

Q27670898-337042CD-5AD3-4E35-8546-B095C33F1B77

Q27670898-400869B1-E473-434B-BA91-DB34D7F909DD

P304

Q27670898-F75ACF58-13FE-4A90-A3BA-8C04C701D397

P31

Q27670898-E799FC75-A0CA-4335-BAF1-4DAAE1BD59BF

P3181

Q27670898-F5C8C818-79E8-474F-BE50-88C073582E7D

P356

Q27670898-D7F42DAF-A7D4-42EE-91B0-FBF9B0BC1F0C

P407

Q27670898-4C0A2B82-2A27-4B0F-A29A-B66F8EDE02F9

P433

Q27670898-035F294D-31B7-4E70-9302-BF5FA3F72C92

P478

Q27670898-822D366B-9DCE-407D-9323-1E05AD963B51

P50

Q27670898-A5AB5E67-35A5-4CFC-B138-51D2202C0692

P577

Q27670898-494AD184-54D7-4398-A3DF-35C4658FE859

P698

Q27670898-4C48A24F-CCB2-4951-9DA5-7DBEC613C730

P921

Q27670898-4BE9D80E-4F66-4224-BD42-2875D48E52FD

P932

Q27670898-50FACA87-27B2-4B78-AE27-B5322C2EC359

P3181

P356

JBC.M111.244632

P1433

Journal of Biological Chemistry

P1476

Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

@en

P2093

Ambrose R Cole

http://www.w3.org/2001/XMLSchema#string

Andrew Purkiss

http://www.w3.org/2001/XMLSchema#string

Charlotte Hodson

http://www.w3.org/2001/XMLSchema#string

Helen Walden

http://www.w3.org/2001/XMLSchema#string

Laurence P C Lewis

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13

UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

The structure of the catalytic subunit FANCL of the Fanconi anemia core complex

Integration, scaling, space-group assignment and post-refinement

MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes

P304

32628-37

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1012828

http://www.w3.org/2001/XMLSchema#string

P356

10.1074/JBC.M111.244632

http://www.w3.org/2001/XMLSchema#string

P407

P433

37

http://www.w3.org/2001/XMLSchema#string

P478

286

http://www.w3.org/2001/XMLSchema#string

P50

P577

2011-09-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

21775430

http://www.w3.org/2001/XMLSchema#string

P921

P932

3173227

http://www.w3.org/2001/XMLSchema#string