LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways
about
Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modulesActivators of G protein signaling in the kidneySpindle orientation in mammalian cerebral cortical developmentEpithelial homeostasisActivators of G protein signaling exhibit broad functionality and define a distinct core signaling triadOriented cell division: new roles in guiding skin wound repair and regenerationOriented divisions, fate decisionsMolecular pathways regulating mitotic spindle orientation in animal cellsMultisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegansStructural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisionsConcomitant binding of Afadin to LGN and F-actin directs planar spindle orientationCrystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from GαiNuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic SpindleCell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation.Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cellsPar3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN.Spindle orientation: what if it goes wrong?Structural basis of diverse membrane target recognitions by ankyrins.Structural evidence for Scc4-dependent localization of cohesin loadingLGN Directs Interphase Endothelial Cell Behavior via the Microtubule Network.The Non-canonical Tetratricopeptide Repeat (TPR) Domain of Fluorescent (FLU) Mediates Complex Formation with Glutamyl-tRNA Reductase.Galpha/LGN-mediated asymmetric spindle positioning does not lead to unequal cleavage of the mother cell in 3-D cultured MDCK cells.Warts phosphorylates mud to promote pins-mediated mitotic spindle orientation in Drosophila, independent of Yorkie.Asymmetric cell divisions in the epidermis.Spindle orientation and epidermal morphogenesis.Polarity and cell division orientation in the cleavage embryo: from worm to human.Analysis and modeling of mitotic spindle orientations in three dimensions.Cell division orientation is coupled to cell-cell adhesion by the E-cadherin/LGN complex.The G-protein regulator LGN modulates the activity of the NO receptor soluble guanylate cyclaseUnreported intrinsic disorder in proteins: Building connections to the literature on IDPs.An oblique view on the role of spindle orientation in vertebrate neurogenesis.On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN.Going vertical: functional role and working principles of the protein Inscuteable in asymmetric cell divisions.Epithelial polarity and spindle orientation: intersecting pathways.Cell Division Modes and Cleavage Planes of Neural Progenitors during Mammalian Cortical Development.Cell adhesion molecule control of planar spindle orientation.The Spindle Orientation Machinery Beyond Mitosis: When Cell Specialization Demands Polarization.Crystallization and X-ray diffraction of LGN in complex with the actin-binding protein afadin.Inscuteable regulates the Pins-Mud spindle orientation pathway.
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P2860
LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
LGN/mInsc and LGN/NuMA Complex ...... /LGN and Gαi/LGN/NuMA Pathways
@ast
LGN/mInsc and LGN/NuMA Complex ...... /LGN and Gαi/LGN/NuMA Pathways
@en
LGN/mInsc and LGN/NuMA Complex ...... /LGN and Gαi/LGN/NuMA Pathways
@nl
type
label
LGN/mInsc and LGN/NuMA Complex ...... /LGN and Gαi/LGN/NuMA Pathways
@ast
LGN/mInsc and LGN/NuMA Complex ...... /LGN and Gαi/LGN/NuMA Pathways
@en
LGN/mInsc and LGN/NuMA Complex ...... /LGN and Gαi/LGN/NuMA Pathways
@nl
prefLabel
LGN/mInsc and LGN/NuMA Complex ...... /LGN and Gαi/LGN/NuMA Pathways
@ast
LGN/mInsc and LGN/NuMA Complex ...... /LGN and Gαi/LGN/NuMA Pathways
@en
LGN/mInsc and LGN/NuMA Complex ...... /LGN and Gαi/LGN/NuMA Pathways
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
LGN/mInsc and LGN/NuMA complex ...... /LGN and Gαi/LGN/NuMA pathways
@en
P2093
Jinwei Zhu
Wenning Wang
Zhen Zheng
Zhuoni Xiao
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2011.07.011
P577
2011-08-01T00:00:00Z