Structural and functional insights into a dodecameric molecular machine - the RuvBL1/RuvBL2 complex
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Substrate recognition and function of the R2TP complex in response to cellular stressMolecular architecture of the ATP-dependent chromatin-remodeling complex SWR1.The AAA+ proteins Pontin and Reptin enter adult age: from understanding their basic biology to the identification of selective inhibitors.RuvbL1 and RuvbL2 enhance aggresome formation and disaggregate amyloid fibrils.The emergence of the conserved AAA+ ATPases Pontin and Reptin on the signaling landscape.Conformational transitions regulate the exposure of a DNA-binding domain in the RuvBL1-RuvBL2 complex.The Structure of the R2TP Complex Defines a Platform for Recruiting Diverse Client Proteins to the HSP90 Molecular Chaperone System.Structure of Yin Yang 1 oligomers that cooperate with RuvBL1-RuvBL2 ATPasesFirst identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assay.Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control.LINKIN, a new transmembrane protein necessary for cell adhesionSubnuclear domain proteins in cancer cells support the functions of RUNX2 in the DNA damage response.Chromosome Missegregation Associated with RUVBL1 DeficiencyThe Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight into the Overall Architecture of the Dodecameric Rvb1/Rvb2 Complex.Mechanism of the AAA+ ATPases pontin and reptin in the biogenesis of H/ACA RNPs.Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage.Integrated microRNA and protein expression analysis reveals novel microRNA regulation of targets in fetal down syndrome.PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination.Lytic water dynamics reveal evolutionarily conserved mechanisms of ATP hydrolysis by TIP49 AAA+ ATPases.Chaperone-like activity of the AAA+ proteins Rvb1 and Rvb2 in the assembly of various complexes.Synergy and antagonism in regulation of recombinant human INO80 chromatin remodeling complexGrifola frondosa Glycoprotein GFG-3a Arrests S phase, Alters Proteome, and Induces Apoptosis in Human Gastric Cancer Cells.Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases.Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin.Regulation of Rvb1/Rvb2 by a Domain within the INO80 Chromatin Remodeling Complex Implicates the Yeast Rvbs as Protein Assembly Chaperones.The Role of Pontin and Reptin in Cellular Physiology and Cancer Etiology.Plasmodium falciparum RuvB proteins: Emerging importance and expectations beyond cell cycle progression.Reptin regulates insulin-stimulated Akt phosphorylation in hepatocellular carcinoma via the regulation of SHP-1/PTPN6.Cryo-EM structures of the human INO80 chromatin-remodeling complex.RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus.Plasmodium falciparum RUVBL3 protein: a novel DNA modifying enzyme and an interacting partner of essential HAT protein MYSTReptin regulates pluripotency of embryonic stem cells and somatic cell reprogramming through Oct4-dependent mechanismX-ray structure of full-length human RuvB-Like 2 - mechanistic insights into coupling between ATP binding and mechanical action
P2860
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P2860
Structural and functional insights into a dodecameric molecular machine - the RuvBL1/RuvBL2 complex
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structural and functional insi ...... ne - the RuvBL1/RuvBL2 complex
@ast
Structural and functional insi ...... ne - the RuvBL1/RuvBL2 complex
@en
Structural and functional insi ...... ne - the RuvBL1/RuvBL2 complex
@nl
type
label
Structural and functional insi ...... ne - the RuvBL1/RuvBL2 complex
@ast
Structural and functional insi ...... ne - the RuvBL1/RuvBL2 complex
@en
Structural and functional insi ...... ne - the RuvBL1/RuvBL2 complex
@nl
prefLabel
Structural and functional insi ...... ne - the RuvBL1/RuvBL2 complex
@ast
Structural and functional insi ...... ne - the RuvBL1/RuvBL2 complex
@en
Structural and functional insi ...... ne - the RuvBL1/RuvBL2 complex
@nl
P2093
P50
P3181
P1476
Structural and functional insi ...... ne - the RuvBL1/RuvBL2 complex
@en
P2093
Filipa G Pinho
Peter Donner
Sabine Gorynia
P304
P3181
P356
10.1016/J.JSB.2011.09.001
P50
P577
2011-12-01T00:00:00Z