Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
about
Programmable DNA-binding proteins from Burkholderia provide a fresh perspective on the TALE-like repeat domainRepeat-containing protein effectors of plant-associated organismsTAL effectors and the executor R genesTranscription activator-like effectors: a toolkit for synthetic biologyMolecular dynamics simulations of DNA-free and DNA-bound TAL effectorsRevisiting the TALE repeatStructural basis for the modular recognition of single-stranded RNA by PPR proteinsDissection of TALE-dependent gene activation reveals that they induce transcription cooperatively and in both orientationsAnnoTALE: bioinformatics tools for identification, annotation, and nomenclature of TALEs from Xanthomonas genomic sequences.Refined requirements for protein regions important for activity of the TALE AvrBs3.Repeat 1 of TAL effectors affects target specificity for the base at position zeroA TAL effector repeat architecture for frameshift binding.megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.The effect of increasing numbers of repeats on TAL effector DNA binding specificityTranscription activator-like effector nucleases (TALENs): a highly efficient and versatile tool for genome editing.Direct observation of TALE protein dynamics reveals a two-state search mechanismDNA-binding proteins from marine bacteria expand the known sequence diversity of TALE-like repeats.Directed evolution of the TALE N-terminal domain for recognition of all 5' bases.TAL effectors specificity stems from negative discrimination.TAL effector specificity for base 0 of the DNA target is altered in a complex, effector- and assay-dependent manner by substitutions for the tryptophan in cryptic repeat -1.Identification of putative TAL effector targets of the citrus canker pathogens shows functional convergence underlying disease development and defense response.TALEored Epigenetics: A DNA-Binding Scaffold for Programmable Epigenome Editing and Analysis.Generation of dTALEs and Libraries of Synthetic TALE-Activated Promoters for Engineering of Gene Regulatory Networks in Plants.A transcription activator-like effector (TALE) induction system mediated by proteolysisQuantitative analysis of TALE-DNA interactions suggests polarity effects.TALE-Like Effectors Are an Ancestral Feature of the Ralstonia solanacearum Species Complex and Converge in DNA Targeting Specificity.Suppression of Xo1-Mediated Disease Resistance in Rice by a Truncated, Non-DNA-Binding TAL Effector of Xanthomonas oryzae.TAL effectors: function, structure, engineering and applications.TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteinsOn the front line: structural insights into plant-pathogen interactions.Conformational elasticity can facilitate TALE-DNA recognitionTargeted genome regulation and modification using transcription activator-like effectors.Technology developments in biological tools for targeted genome surgery.TAL effectors--pathogen strategies and plant resistance engineering.Non-RVD mutations that enhance the dynamics of the TAL repeat array along the superhelical axis improve TALEN genome editing efficacy.TAL effectors: tools for DNA targeting.Synthetic TAL effectors for targeted enhancement of transgene expression in plants.From dead leaf, to new life: TAL effectors as tools for synthetic biology.Broken TALEs: Transcription Activator-like Effectors Populate Partly Folded States.Fine and Predictable Tuning of TALEN Gene Editing Targeting for Improved T Cell Adoptive Immunotherapy.
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P2860
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
@ast
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
@en
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
@nl
type
label
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
@ast
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
@en
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
@nl
prefLabel
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
@ast
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
@en
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
@nl
P2093
P2860
P921
P3181
P356
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P1476
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region
@en
P2093
Haishan Gao
Jijie Chai
Xiaojing Wu
P2860
P2888
P304
P3181
P356
10.1038/CR.2012.156
P577
2012-12-01T00:00:00Z
P5875
P6179
1051559534