Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905)

Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905)

Item
http://www.wikidata.org/entity/Q27675472
Plk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell linesCurrent progress and future perspectives in the development of anti-polo-like kinase 1 therapeutic agents.Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1.Discovery of Novel Antiangiogenic Marine Natural Product Scaffolds.Small molecule-mediated up-regulation of microRNA targeting a key cell death modulator BNIP3 improves cardiac function following ischemic injury.Recent Advances and New Strategies in Targeting Plk1 for Anticancer TherapyApplications of Palladium-Catalyzed C-N Cross-Coupling Reactions.Molecular modeling and structure-based drug discovery approach reveals protein kinases as off-targets for novel anticancer drug RH1.A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.Monitoring and inhibition of Plk1: amphiphilic porphyrin conjugated Plk1 specific peptides for its imaging and anti-tumor function.
P2860

Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905)

Item
http://www.wikidata.org/entity/Q27675472
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Discovery of a potent and oral ...... f Polo-like kinase 1 (MLN0905)
@ast
Discovery of a potent and oral ...... f Polo-like kinase 1 (MLN0905)
@en
Discovery of a potent and oral ...... f Polo-like kinase 1 (MLN0905)
@nl
type
label
Discovery of a potent and oral ...... f Polo-like kinase 1 (MLN0905)
@ast
Discovery of a potent and oral ...... f Polo-like kinase 1 (MLN0905)
@en
Discovery of a potent and oral ...... f Polo-like kinase 1 (MLN0905)
@nl
prefLabel
Discovery of a potent and oral ...... f Polo-like kinase 1 (MLN0905)
@ast
Discovery of a potent and oral ...... f Polo-like kinase 1 (MLN0905)
@en
Discovery of a potent and oral ...... f Polo-like kinase 1 (MLN0905)
@nl
P1433
P1476
P2093
P304
P31
P3181
P356
P407
P433
P478
P577
P698
P3181
P356
P1433
P1476
Discovery of a potent and oral ...... f Polo-like kinase 1 (MLN0905)
@en
P2093
P304
P31
P3181
P356
P407
P433
P478
P577
P698