Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer
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Why reinvent the wheel? Building new proteins based on ready-made partsProtein design: toward functional metalloenzymesComputational Design of an Unnatural Amino Acid Dependent Metalloprotein with Atomic Level AccuracyAccurate design of co-assembling multi-component protein nanomaterialsA designed supramolecular protein assembly with in vivo enzymatic activityBiomineralization of a Cadmium Chloride Nanocrystal by a Designed Symmetrical ProteinOn the predictability of the orientation of protein domains joined by a spanning alpha-helical linkerAccurate design of megadalton-scale two-component icosahedral protein complexesAngiopoietin-like protein 4 inhibition of lipoprotein lipase: evidence for reversible complex formationA structural bioinformatics approach for identifying proteins predisposed to bind linear epitopes on pre-selected target proteinsDesigning hydrolytic zinc metalloenzymesComputational approaches for rational design of proteins with novel functionalitiesComputational de novo design of a four-helix bundle protein--DND_4HB.Probing the minimal determinants of zinc binding with computational protein designComputational protein engineering: bridging the gap between rational design and laboratory evolution.The Protein Structure Initiative: achievements and visions for the future.Combined computational design of a zinc-binding site and a protein-protein interaction: one open zinc coordination site was not a robust hotspot for de novo ubiquitin bindingStrategies to control the binding mode of de novo designed protein interactions.Catalysis by a de novo zinc-mediated protein interface: implications for natural enzyme evolution and rational enzyme engineering.Computational design and experimental verification of a symmetric protein homodimer.Computational strategies for the design of new enzymatic functionsA Suite of Engineered GFP Molecules for Oligomeric Scaffolding.Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expressionDesign of a hyperstable 60-subunit protein dodecahedron. [corrected]Designing functional metalloproteins: from structural to catalytic metal sites.Metal-Directed Design of Supramolecular Protein Assemblies.Computational design of a homotrimeric metalloprotein with a trisbipyridyl core.An improved Protein G with higher affinity for human/rabbit IgG Fc domains exploiting a computationally designed polar network.Computational design of self-assembling cyclic protein homo-oligomers.Emerging themes in the computational design of novel enzymes and protein-protein interfaces.Using anchoring motifs for the computational design of protein-protein interactions.AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences.A comparison of successful and failed protein interface designs highlights the challenges of designing buried hydrogen bonds.Femtomolar Zn(II) affinity of minimal zinc hook peptides--a promising small tag for protein engineering.Using thermal scanning assays to test protein-protein interactions of inner-ear cadherins.De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles.Creation of artificial protein-protein interactions using α-helices as interfaces.Rational Design of Domain-Swapping-Based c-Type Cytochrome Heterodimers by Using Chimeric Proteins.Incorporating an allosteric regulatory site in an antibody through backbone design.Protocols for Requirement-Driven Protein Design in the Rosetta Modeling Program.
P2860
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P2860
Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Metal-Mediated Affinity and Or ...... lly Designed Protein Homodimer
@ast
Metal-Mediated Affinity and Or ...... lly Designed Protein Homodimer
@en
Metal-Mediated Affinity and Or ...... lly Designed Protein Homodimer
@nl
type
label
Metal-Mediated Affinity and Or ...... lly Designed Protein Homodimer
@ast
Metal-Mediated Affinity and Or ...... lly Designed Protein Homodimer
@en
Metal-Mediated Affinity and Or ...... lly Designed Protein Homodimer
@nl
prefLabel
Metal-Mediated Affinity and Or ...... lly Designed Protein Homodimer
@ast
Metal-Mediated Affinity and Or ...... lly Designed Protein Homodimer
@en
Metal-Mediated Affinity and Or ...... lly Designed Protein Homodimer
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Metal-Mediated Affinity and Or ...... lly Designed Protein Homodimer
@en
P2093
Bryan S Der
Jeffrey L Mills
Michael J Miley
P2860
P304
P3181
P356
10.1021/JA208015J
P407
P577
2012-01-11T00:00:00Z