Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel.
about
Optogenetic techniques for the study of native potassium channelsMechanosensitive channels: feeling tension in a world under pressureTemperature sensitivity of two-pore (K2P) potassium channelsK2P channel gating mechanisms revealed by structures of TREK-2 and a complex with ProzacFeeling the hidden mechanical forces in lipid bilayer is an original sensePolymodal activation of the TREK-2 K2P channel produces structurally distinct open statesTransmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.Bacterial voltage-gated sodium channels (BacNa(V)s) from the soil, sea, and salt lakes enlighten molecular mechanisms of electrical signaling and pharmacology in the brain and heart.Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels.Molecular modeling of a tandem two pore domain potassium channel reveals a putative binding site for general anesthetics.Overexpression of membrane proteins from higher eukaryotes in yeasts.Differential sensitivity of TREK-1, TREK-2 and TRAAK background potassium channels to the polycationic dye ruthenium red.Scanning MscL Channels with Targeted Post-Translational Modifications for Functional Alterations.A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.Conduits of life's spark: a perspective on ion channel research since the birth of neuron.Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+ channels.Potassium channels: structures, diseases, and modulators.Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia.The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements.K₂p channels in plants and animals.The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias.Two-pore domain potassium channels: potential therapeutic targets for the treatment of pain.The role of protein-protein interactions in the intracellular traffic of the potassium channels TASK-1 and TASK-3.Much more than a leak: structure and function of K₂p-channels.Structure of potassium channels.How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2.K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.Gating, Regulation, and Structure in K2P K+ Channels: In Varietate Concordia?Functional mutagenesis screens reveal the 'cap structure' formation in disulfide-bridge free TASK channels.Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel.An allosteric ligand-binding site in the extracellular cap of K2P channels.Mechanosensitive Ion Channels in Cardiovascular PhysiologyPhysical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.Asymmetric mechanosensitivity in a eukaryotic ion channel.The effects of stretch activation on ionic selectivity of the TREK-2 K2P K+ channel.Understanding the Cap Structure in K2P Channels.The Insensitivity of TASK-3 K₂P Channels to External Tetraethylammonium (TEA) Partially Depends on the Cap Structure
P2860
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P2860
Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Domain-swapped chain connectiv ...... of the human TRAAK K+ channel
@nl
Domain-swapped chain connectiv ...... of the human TRAAK K+ channel.
@ast
Domain-swapped chain connectiv ...... of the human TRAAK K+ channel.
@en
type
label
Domain-swapped chain connectiv ...... of the human TRAAK K+ channel
@nl
Domain-swapped chain connectiv ...... of the human TRAAK K+ channel.
@ast
Domain-swapped chain connectiv ...... of the human TRAAK K+ channel.
@en
prefLabel
Domain-swapped chain connectiv ...... of the human TRAAK K+ channel
@nl
Domain-swapped chain connectiv ...... of the human TRAAK K+ channel.
@ast
Domain-swapped chain connectiv ...... of the human TRAAK K+ channel.
@en
P2860
P3181
P356
P1476
Domain-swapped chain connectiv ...... of the human TRAAK K+ channel.
@en
P2093
Ernest B Campbell
Stephen G Brohawn
P2860
P304
P3181
P356
10.1073/PNAS.1218950110
P407
P577
2013-01-22T00:00:00Z