Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase - Wikidata - wikimedia - TriplyDB

Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

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Computational drug design strategies applied to the modelling of human immunodeficiency virus-1 reverse transcriptase inhibitors Site-specific infrared probes of proteins Detecting Allosteric Sites of HIV-1 Reverse Transcriptase by X-ray Crystallographic Fragment Screening Structure of a Dihydroxycoumarin Active-Site Inhibitor in Complex with the RNase H Domain of HIV-1 Reverse Transcriptase and Structure–Activity Analysis of Inhibitor Analogs A structural and dynamic investigation of the inhibition of catalase by nitric oxide Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target Watching Proteins Wiggle: Mapping Structures with Two-Dimensional Infrared Spectroscopy.2D IR spectroscopy using four-wave mixing, pulse shaping, and IR upconversion: a quantitative comparison.Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO)HIV-1 reverse transcriptase and antiviral drug resistance. Part 1.2D IR spectroscopy reveals the role of water in the binding of channel-blocking drugs to the influenza M2 channel.Ultrafast 2D IR microscopy Multidimensional infrared spectroscopy reveals the vibrational and solvation dynamics of isoniazid.Broadband two dimensional infrared spectroscopy of cyclic amide 2-Pyrrolidinone.Applications of two-dimensional infrared spectroscopy Advantages of crystallographic fragment screening: functional and mechanistic insights from a powerful platform for efficient drug discovery.Switches of hydrogen bonds during ligand-protein association processes determine binding kinetics.From Ultrafast Structure Determination to Steering Reactions: Mixed IR/Non-IR Multidimensional Vibrational Spectroscopies.Molecular insight on the binding of NNRTI to K103N mutated HIV-1 RT: molecular dynamics simulations and dynamic pharmacophore analysis.Application of Site-Specific Spin Labeling for NMR Detecting Inhibitor-Induced Conformational Change of HIV-1 Reverse Transcriptase.Line shape analysis of two-dimensional infrared spectra 6-Cyclohexylmethyl-3-hydroxypyrimidine-2,4-dione as an inhibitor scaffold of HIV reverase transcriptase: Impacts of the 3-OH on inhibiting RNase H and polymerase.Ultrafast infrared spectroscopy reveals water-mediated coherent dynamics in an enzyme active site.Quantum process tomography quantifies coherence transfer dynamics in vibrational exciton.Quantum Beats and Coherence Decay in Degenerate States Split by Solvation.Effects of the protonation state in the interaction of an HIV-1 reverse transcriptase (RT) amino acid, Lys101, and a non nucleoside RT inhibitor, GW420867X.Drug-protein interactions: Mechanisms of potency.Robin Main Hochstrasser (1931–2013), giant of physical chemistry.Capturing the photo-signaling state of a photoreceptor in a steady-state fashion by binding a transition metal complex.Ultrafast structural molecular dynamics investigated with 2D infrared spectroscopy methods.HIV-1 Uncoating and Reverse Transcription Require eEF1A Binding to Surface-Exposed Acidic Residues of the Reverse Transcriptase Thumb Domain.Couplings between hierarchical conformational dynamics from multi-time correlation functions and two-dimensional lifetime spectra: Application to adenylate kinase.Communication: Nanosecond folding dynamics of an alpha helix: Time-dependent 2D-IR cross peaks observed using polarization-sensitive dispersed pump-probe spectroscopy

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Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

http://www.wikidata.org/entity/Q27676461

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2013 nî lūn-bûn

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2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

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Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

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Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

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Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

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Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

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Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

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Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

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Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

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Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

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Nature Chemistry

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Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase

@en

P2093

Daniel G Kuroda

http://www.w3.org/2001/XMLSchema#string

Disha Patel

http://www.w3.org/2001/XMLSchema#string

J Reddy Challa

http://www.w3.org/2001/XMLSchema#string

Joseph D Bauman

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Kalyan Das

http://www.w3.org/2001/XMLSchema#string

Robin M Hochstrasser

http://www.w3.org/2001/XMLSchema#string

Thomas Troxler

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P2860

Two-dimensional infrared spectra reveal relaxation of the nonnucleoside inhibitor TMC278 complexed with HIV-1 reverse transcriptase

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Comparison of simple potential functions for simulating liquid water

Processing of X-ray diffraction data collected in oscillation mode

High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations.

Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design

Features and development of Coot

Development and testing of a general amber force field

A genetically encoded infrared probe.

Chemical exchange 2D IR of hydrogen-bond making and breaking.

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5

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1000276339

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3607437

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