Engineering and structural characterization of a linear polyubiquitin-specific antibody
about
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesisOTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitinMass Spectrometry-Based Proteomics for Investigating DNA Damage-Associated Protein UbiquitylationUbiquitin modificationsRegulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULINOptimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblottingNew conformations of linear polyubiquitin chains from crystallographic and solution-scattering studies expand the conformational space of polyubiquitinGenetically Directed Production of Recombinant, Isosteric and Nonhydrolysable Ubiquitin ConjugatesRegulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteinsCharacterizing ubiquitination sites by peptide-based immunoaffinity enrichment.TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structuresThe linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation.Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling.The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease.Middle-down mass spectrometry enables characterization of branched ubiquitin chains.TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway ActivationHuman HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.Ubiquitylation of nuclear receptors: new linkages and therapeutic implications.Posttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain FormationThe Colossus of ubiquitylation: decrypting a cellular code.Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral PathogenesisUsing the ubiquitin-modified proteome to monitor protein homeostasis function.Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells.Post-translational regulation of inflammasomes.Unraveling the ubiquitin-regulated signaling networks by mass spectrometry-based proteomics.DUBs, the regulation of cell identity and disease.SPATA2 promotes CYLD activity and regulates TNF-induced NF-κB signaling and cell death.The increasing complexity of the ubiquitin code.Assembly and regulation of ASC specks.An emerging role for the ribosome as a nexus for post-translational modifications.Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest).Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells.Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation.Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.The ubiquitin conjugating enzyme UBE2L3 regulates TNFα-induced linear ubiquitinationLys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling.N-methylation of isopeptide bond as a strategy to resist deubiquitinases.Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defence.
P2860
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P2860
Engineering and structural characterization of a linear polyubiquitin-specific antibody
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Engineering and structural characterization of a linear polyubiquitin-specific antibody
@ast
Engineering and structural characterization of a linear polyubiquitin-specific antibody
@en
Engineering and structural characterization of a linear polyubiquitin-specific antibody
@nl
type
label
Engineering and structural characterization of a linear polyubiquitin-specific antibody
@ast
Engineering and structural characterization of a linear polyubiquitin-specific antibody
@en
Engineering and structural characterization of a linear polyubiquitin-specific antibody
@nl
prefLabel
Engineering and structural characterization of a linear polyubiquitin-specific antibody
@ast
Engineering and structural characterization of a linear polyubiquitin-specific antibody
@en
Engineering and structural characterization of a linear polyubiquitin-specific antibody
@nl
P2093
P3181
P1476
Engineering and structural characterization of a linear polyubiquitin-specific antibody
@en
P2093
Christine Yu
Donald S Kirkpatrick
Ken C Dong
Lilian Phu
Marissa L Matsumoto
Rami N Hannoush
Robert F Kelley
Sarah G Hymowitz
Vishva M Dixit
Xinxin Gao
P304
P3181
P356
10.1016/J.JMB.2011.12.053
P407
P577
2012-05-04T00:00:00Z