Insights into congenital stationary night blindness based on the structure of G90D rhodopsin
about
Large-scale production and protein engineering of G protein-coupled receptors for structural studiesConstitutively active rhodopsin and retinal diseaseStructural role of the T94I rhodopsin mutation in congenital stationary night blindnessTransmembrane signal transduction by peptide hormones via family B G protein-coupled receptorsChemistry and biology of the initial steps in vision: the Friedenwald lecture.The role of experimental and computational structural approaches in 7TM drug discovery.A truncated form of rod photoreceptor PDE6 β-subunit causes autosomal dominant congenital stationary night blindness by interfering with the inhibitory activity of the γ-subunit.Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein.Stabilization of G protein-coupled receptors by point mutations.Buried ionizable networks are an ancient hallmark of G protein-coupled receptor activationTime-resolved structural studies with serial crystallography: A new light on retinal proteins.The G protein-coupled receptor rhodopsin: a historical perspectiveFunctional map of arrestin binding to phosphorylated opsin, with and without agonist.Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 bindingStructure and dynamics of a constitutively active neurotensin receptor.Functional map of arrestin-1 at single amino acid resolutionMicrobial and animal rhodopsins: structures, functions, and molecular mechanisms.Extensive shape shifting underlies functional versatility of arrestins.The Activation Pathway of Human Rhodopsin in Comparison to Bovine Rhodopsin.Graph analysis of β2 adrenergic receptor structures: a "social network" of GPCR residues.Self-association of arrestin family members.Rapid degeneration of rod photoreceptors expressing self-association-deficient arrestin-1 mutant.Arrestins in apoptosis.Structural biology. Viral chemokine mimicry.Enhanced phosphorylation-independent arrestins and gene therapy.The rhodopsin-arrestin-1 interaction in bicelles.Ligand channel in pharmacologically stabilized rhodopsin.In silico studies targeting G-protein coupled receptors for drug research against Parkinson's disease.A Novel Heterozygous Missense Mutation in GNAT1 Leads to Autosomal Dominant Riggs Type of Congenital Stationary Night Blindness.G protein-coupled receptors: the evolution of structural insight.Conformational activation of visual rhodopsin in native disc membranesCrystal structure of rhodopsin in complex with a mini-G sheds light on the principles of G protein selectivity
P2860
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P2860
Insights into congenital stationary night blindness based on the structure of G90D rhodopsin
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Insights into congenital stati ...... he structure of G90D rhodopsin
@ast
Insights into congenital stati ...... he structure of G90D rhodopsin
@en
Insights into congenital stati ...... he structure of G90D rhodopsin
@nl
type
label
Insights into congenital stati ...... he structure of G90D rhodopsin
@ast
Insights into congenital stati ...... he structure of G90D rhodopsin
@en
Insights into congenital stati ...... he structure of G90D rhodopsin
@nl
prefLabel
Insights into congenital stati ...... he structure of G90D rhodopsin
@ast
Insights into congenital stati ...... he structure of G90D rhodopsin
@en
Insights into congenital stati ...... he structure of G90D rhodopsin
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Insights into congenital stati ...... he structure of G90D rhodopsin
@en
P2093
Ankita Singhal
Gebhard F X Schertler
Joerg Standfuss
John J G Tesmer
Kristoff T Homan
Martin K Ostermaier
Sergey A Vishnivetskiy
Valérie Panneels
P2860
P3181
P356
10.1038/EMBOR.2013.44
P577
2013-06-01T00:00:00Z