Structure and dynamics of the M3 muscarinic acetylcholine receptor - Wikidata - wikimedia - TriplyDB

Structure and dynamics of the M3 muscarinic acetylcholine receptor

Structure and dynamics of the M3 muscarinic acetylcholine receptor

http://www.wikidata.org/entity/Q27677433

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Activation and allosteric modulation of a muscarinic acetylcholine receptor Revealing Atomic-Level Mechanisms of Protein Allostery with Molecular Dynamics Simulations G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRs Structural Studies of G Protein-Coupled Receptors The Camerino symposium series (1978-2013): a privileged observatory of receptorology development Post-expression strategies for structural investigations of membrane proteins.Large-scale production and protein engineering of G protein-coupled receptors for structural studies New insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptors Muscarinic acetylcholine receptor X-ray structures: potential implications for drug development Exploring the role of receptor flexibility in structure-based drug discovery Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors Endogenous lipid activated G protein-coupled receptors: emerging structural features from crystallography and molecular dynamics simulations A constitutively active G protein-coupled acetylcholine receptor regulates motility of larval Schistosoma mansoni Effects of different tissue microenvironments on gene expression in breast cancer cells The pathway of ligand entry from the membrane bilayer to a lipid G protein-coupled receptor.Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor Conopeptide -TIA Defines a New Allosteric Site on the Extracellular Surface of the 1B-Adrenoceptor Structural Characterization of an LPA1 Second Extracellular Loop Mimetic with a Self-Assembling Coiled-Coil Folding Constraint Biophysical Fragment Screening of the β 1 -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design Crystal structure of the µ-opioid receptor bound to a morphinan antagonist Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant Multiple conformational states in retrospective virtual screening – homology models vs. crystal structures: beta-2 adrenergic receptor case study Generic GPCR residue numbers - aligning topology maps while minding the gaps Structural insights into ligand recognition and selectivity for classes A, B, and C GPCRs Binding of N-methylscopolamine to the extracellular domain of muscarinic acetylcholine receptors Assessment and challenges of ligand docking into comparative models of G-protein coupled receptors A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity The Repellent DEET Potentiates Carbamate Effects via Insect Muscarinic Receptor Interactions: An Alternative Strategy to Control Insect Vector-Borne Diseases Structure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional Implications Sequence, structure and ligand binding evolution of rhodopsin-like G protein-coupled receptors: a crystal structure-based phylogenetic analysis Membrane protein structure determination using crystallography and lipidic mesophases: recent advances and successes.Invited review: GPCR structural characterization: Using fragments as building blocks to determine a complete structure.Novel Xylene-Linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation The role of experimental and computational structural approaches in 7TM drug discovery.Structure and function of serotonin G protein-coupled receptors.Common molecular mechanism of the hepatic lesion and the cardiac parasympathetic regulation in chronic hepatitis C infection: a critical role for the muscarinic receptor type 3.Exploring the mechanism of F282L mutation-caused constitutive activity of GPCR by a computational study.Detection of Side Chain Rearrangements Mediating the Motions of Transmembrane Helices in Molecular Dynamics Simulations of G Protein-Coupled Receptors.Compound activity prediction using models of binding pockets or ligand properties in 3D.

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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2012 nî lūn-bûn

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2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2012 թվականի փետրվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

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Daniel H Arlow

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Daniel M Rosenbaum

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Tong Liu

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P2860

Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders

Structure and function of an irreversible agonist-β(2) adrenoceptor complex

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fields

Crystal structure of the β2 adrenergic receptor-Gs protein complex

Identification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observations

PHENIX: a comprehensive Python-based system for macromolecular structure solution

All-atom empirical potential for molecular modeling and dynamics studies of proteins

VMD: visual molecular dynamics

MOLPROBITY: structure validation and all-atom contact analysis for nucleic acids and their complexes

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