Structural basis and selectivity of tankyrase inhibition by a Wnt signaling inhibitor WIKI4
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Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human CellsChemical Disruption of Wnt-dependent Cell Fate Decision-making Mechanisms in Cancer and Regenerative MedicineStructure-Based Design of 2-Aminopyridine Oxazolidinones as Potent and Selective Tankyrase InhibitorsEvaluation and Structural Basis for the Inhibition of Tankyrases by PARP Inhibitorspara-Substituted 2-phenyl-3,4-dihydroquinazolin-4-ones as potent and selective tankyrase inhibitorsIdentifying Family-Member-Specific Targets of Mono-ARTDs by Using a Chemical Genetics Approach.Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics.The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2Tankyrases as drug targets.Tankyrases: structure, function and therapeutic implications in cancer.Recent advances in the structure-based rational design of TNKSIs.Concepts and Molecular Aspects in the Polypharmacology of PARP-1 Inhibitors.Identifying Direct Protein Targets of Poly-ADP-Ribose Polymerases (PARPs) Using Engineered PARP Variants-Orthogonal Nicotinamide Adenine Dinucleotide (NAD+) Analog Pairs.Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.Discovery of new dual binding TNKS inhibitors of Wnt signaling inhibition by pharmacophore modeling, molecular docking and bioassay.
P2860
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P2860
Structural basis and selectivity of tankyrase inhibition by a Wnt signaling inhibitor WIKI4
description
2013 nî lūn-bûn
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2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
@ja
2013年論文
@yue
2013年論文
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2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
Structural basis and selectivi ...... Wnt signaling inhibitor WIKI4
@ast
Structural basis and selectivi ...... Wnt signaling inhibitor WIKI4
@en
Structural basis and selectivi ...... Wnt signaling inhibitor WIKI4
@nl
type
label
Structural basis and selectivi ...... Wnt signaling inhibitor WIKI4
@ast
Structural basis and selectivi ...... Wnt signaling inhibitor WIKI4
@en
Structural basis and selectivi ...... Wnt signaling inhibitor WIKI4
@nl
prefLabel
Structural basis and selectivi ...... Wnt signaling inhibitor WIKI4
@ast
Structural basis and selectivi ...... Wnt signaling inhibitor WIKI4
@en
Structural basis and selectivi ...... Wnt signaling inhibitor WIKI4
@nl
P2093
P2860
P1433
P1476
Structural Basis and Selectivi ...... Wnt Signaling Inhibitor WIKI4
@en
P2093
Ezeogo Obaji
Hao-Wei Lee
Harikanth Venkannagari
Mohit Narwal
Teemu Haikarainen
Yves Nkizinkiko
P2860
P304
P356
10.1371/JOURNAL.PONE.0065404
P407
P50
P577
2013-01-01T00:00:00Z