Exposure of R169 controls protein C activation and autoactivation - Wikidata - wikimedia - TriplyDB

Exposure of R169 controls protein C activation and autoactivation

Exposure of R169 controls protein C activation and autoactivation

http://www.wikidata.org/entity/Q27678741

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Autoactivation of Thrombin Precursors An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides Why Ser and not Thr brokers catalysis in the trypsin fold WEDGE: an anticoagulant thrombin mutant produced by autoactivation.The Importance of Exosite Interactions for Substrate Cleavage by Human Thrombin.Kinetic dissection of the pre-existing conformational equilibrium in the trypsin fold.Histone H4 promotes prothrombin autoactivation.Down-regulation of the clotting cascade by the protein C pathway Rational Design of Protein C Activators.Non-canonical proteolytic activation of human prothrombin by subtilisin from Bacillus subtilis may shift the procoagulant-anticoagulant equilibrium toward thrombosis.β2 -Glycoprotein I binds to thrombin and selectively inhibits the enzyme procoagulant functions.Interplay between conformational selection and zymogen activation.

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Exposure of R169 controls protein C activation and autoactivation

http://www.wikidata.org/entity/Q27678741

description

2012 nî lūn-bûn

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2012 թվականի հուլիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Exposure of R169 controls protein C activation and autoactivation

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Exposure of R169 controls protein C activation and autoactivation

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Exposure of R169 controls protein C activation and autoactivation

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Exposure of R169 controls protein C activation and autoactivation

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Exposure of R169 controls protein C activation and autoactivation

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Exposure of R169 controls protein C activation and autoactivation

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Exposure of R169 controls protein C activation and autoactivation

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Exposure of R169 controls protein C activation and autoactivation

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Exposure of R169 controls protein C activation and autoactivation

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Exposure of R169 controls protein C activation and autoactivation

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Enrico Di Cera

http://www.w3.org/2001/XMLSchema#string

Nicola Pozzi

http://www.w3.org/2001/XMLSchema#string

Sergio Barranco-Medina

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Zhiwei Chen

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Structures of C3b in complex with factors B and D give insight into complement convertase formation

Processing of X-ray diffraction data collected in oscillation mode

Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

Interaction of the factor XIII activation peptide with alpha -thrombin. Crystal structure of its enzyme-substrate analog complex

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

Molecular basis of thrombomodulin activation of slow thrombin

Crystal Structure of Thrombin Bound to the Uncleaved Extracellular Fragment of PAR1

Crystal Structures of Prethrombin-2 Reveal Alternative Conformations under Identical Solution Conditions and the Mechanism of Zymogen Activation

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10.1182/BLOOD-2012-03-415323

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