The Mode of Inhibitor Binding to Peptidyl-tRNA Hydrolase: Binding Studies and Structure Determination of Unbound and Bound Peptidyl-tRNA Hydrolase from Acinetobacter baumannii
about
Recombinant production, crystallization and X-ray crystallographic structure determination of peptidyl-tRNA hydrolase fromSalmonella typhimuriumStructural and binding studies of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa provide a platform for the structure-based inhibitor design against peptidyl-tRNA hydrolaseCrystal structure of Staphylococcus aureus peptidyl-tRNA hydrolase at a 2.25 Å resolutionUnraveling the stereochemical and dynamic aspects of the catalytic site of bacterial peptidyl-tRNA hydrolase.Crystal structure of peptidyl-tRNA hydrolase from a Gram-positive bacterium, Streptococcus pyogenes at 2.19 Å resolution shows the closed structure of the substrate-binding cleft.Small Molecule Docking Supports Broad and Narrow Spectrum Potential for the Inhibition of the Novel Antibiotic Target Bacterial Pth1.Miscoding-induced stalling of substrate translocation on the bacterial ribosome.
P2860
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P2860
The Mode of Inhibitor Binding to Peptidyl-tRNA Hydrolase: Binding Studies and Structure Determination of Unbound and Bound Peptidyl-tRNA Hydrolase from Acinetobacter baumannii
description
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2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
The Mode of Inhibitor Binding ...... e from Acinetobacter baumannii
@ast
The Mode of Inhibitor Binding ...... e from Acinetobacter baumannii
@en
The Mode of Inhibitor Binding ...... e from Acinetobacter baumannii
@nl
type
label
The Mode of Inhibitor Binding ...... e from Acinetobacter baumannii
@ast
The Mode of Inhibitor Binding ...... e from Acinetobacter baumannii
@en
The Mode of Inhibitor Binding ...... e from Acinetobacter baumannii
@nl
prefLabel
The Mode of Inhibitor Binding ...... e from Acinetobacter baumannii
@ast
The Mode of Inhibitor Binding ...... e from Acinetobacter baumannii
@en
The Mode of Inhibitor Binding ...... e from Acinetobacter baumannii
@nl
P2093
P2860
P3181
P1433
P1476
The Mode of Inhibitor Binding ...... e from Acinetobacter baumannii
@en
P2093
Ashish Arora
Avinash Singh
Nagendra Singh
Sanket Kaushik
Shavait Yamini
Sujata Sharma
Tej P Singh
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0067547
P407
P50
P577
2013-01-01T00:00:00Z