Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
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Alkaliphilic Bacteria with Impact on Industrial Applications, Concepts of Early Life Forms, and Bioenergetics of ATP SynthesisNew Updates Pertaining to Drug Delivery of Local Anesthetics in Particular Bupivacaine Using Lipid NanoparticlesThe hitchhiker's guide to the voltage-gated sodium channel galaxyVoltage-gated sodium channels and cancer: is excitability their primary role?Computational studies of marine toxins targeting ion channelsFrom foe to friend: using animal toxins to investigate ion channel functionThe Hodgkin-Huxley heritage: from channels to circuitsTheoretical and simulation studies on voltage-gated sodium channelsIon channels as drug targets in central nervous system disordersNa+ channel function, regulation, structure, trafficking and sequestrationProton channel models filling the gap between experimental data and the structural rationaleStructure and function of μ-conotoxins, peptide-based sodium channel blockers with analgesic activityStructural Refinement of Proteins by Restrained Molecular Dynamics Simulations with Non-interacting Molecular Fragments.Different inward and outward conduction mechanisms in NaVMs suggested by molecular dynamics simulationsExploring volatile general anesthetic binding to a closed membrane-bound bacterial voltage-gated sodium channel via computationStructural asymmetry in the magnesium channel CorA points to sequential allosteric regulation.Role of the C-terminal domain in the structure and function of tetrameric sodium channels.Structure of a Prokaryotic Sodium Channel Pore Reveals Essential Gating Elements and an Outer Ion Binding Site Common to Eukaryotic ChannelsStructural basis for Ca2+ selectivity of a voltage-gated calcium channelProkaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonismStructures of KcsA in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding SiteStructural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonistStructural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugsDeciphering voltage-gated Na(+) and Ca(2+) channels by studying prokaryotic ancestorsStructural Basis for Pharmacology of Voltage-Gated Sodium and Calcium ChannelsPost-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmiasLocating the route of entry and binding sites of benzocaine and phenytoin in a bacterial voltage gated sodium channelComparison of Gating Properties and Use-Dependent Block of Nav1.5 and Nav1.7 Channels by Anti-Arrhythmics Mexiletine and LidocaineKCNE1 induces fenestration in the Kv7.1/KCNE1 channel complex that allows for highly specific pharmacological targetingStructure and function of voltage-gated sodium channels at atomic resolution.Exploring the structure of the voltage-gated Na+ channel by an engineered drug access pathway to the receptor site for local anesthetics.Predicting a double mutant in the twilight zone of low homology modeling for the skeletal muscle voltage-gated sodium channel subunit beta-1 (Nav1.4 β1).Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.Cooperative activation of the T-type CaV3.2 channel: interaction between Domains II and III.Minimization of extracellular space as a driving force in prokaryote association and the origin of eukaryotes.Differential lipid dependence of the function of bacterial sodium channelsModular organization of α-toxins from scorpion venom mirrors domain structure of their targets, sodium channels.Visualizing cyclic peptide hydration at the single-molecule levelIon conduction and conformational flexibility of a bacterial voltage-gated sodium channel.Ankyrin-G directly binds to kinesin-1 to transport voltage-gated Na+ channels into axons.
P2860
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P2860
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
@ast
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
@en
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
@nl
type
label
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
@ast
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
@en
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
@nl
prefLabel
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
@ast
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
@en
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
@nl
P2093
P2860
P3181
P356
P1433
P1476
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
@en
P2093
Jian Payandeh
Ning Zheng
Tamer M Gamal El-Din
Todd Scheuer
William A Catterall
P2860
P2888
P3181
P356
10.1038/NATURE11077
P407
P577
2012-05-20T00:00:00Z
P5875
P6179
1012090265