Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase
about
Targeting the ubiquitin pathway for cancer treatmentChemical chronobiology: Toward drugs manipulating time.Emerging models for the molecular basis of mammalian circadian timingA Cryptochrome 2 mutation yields advanced sleep phase in humansFAD Regulates CRYPTOCHROME Protein Stability and Circadian Clock in Mice.ATP binding turns plant cryptochrome into an efficient natural photoswitchMolecular assembly of the period-cryptochrome circadian transcriptional repressor complex.CRY2 and FBXL3 Cooperatively Degrade c-MYC.C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock.Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock.Small molecule therapeutics targeting F-box proteins in cancer.Clock-Enhancing Small Molecules and Potential Applications in Chronic Diseases and Aging.Photochemistry of flavoprotein light sensors.SCF ubiquitin ligase-targeted therapies.Residues at a Single Site Differentiate Animal Cryptochromes from Cyclobutane Pyrimidine Dimer Photolyases by Affecting the Proteins' Preferences for Reduced FAD.How is the inner circadian clock controlled by interactive clock proteins?: Structural analysis of clock proteins elucidates their physiological role.Animal Cryptochromes: Divergent Roles in Light Perception, Circadian Timekeeping and Beyond.Transcriptional architecture of the mammalian circadian clock.Unique Aspects of Cryptochrome in Chronobiology and Metabolism, Pancreatic β-Cell Dysfunction, and Regeneration: Research into Cysteine414-Alanine Mutant CRY1.Chromatin Dynamics of Circadian Transcription.Specific targeting of the deubiquitinase and E3 ligase families with engineered ubiquitin variants.Development and Therapeutic Potential of Small-Molecule Modulators of Circadian Systems.
P2860
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P2860
Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Crystal structure of mammalian ...... etitor of its ubiquitin ligase
@ast
Crystal structure of mammalian ...... etitor of its ubiquitin ligase
@en
Crystal structure of mammalian ...... etitor of its ubiquitin ligase
@nl
type
label
Crystal structure of mammalian ...... etitor of its ubiquitin ligase
@ast
Crystal structure of mammalian ...... etitor of its ubiquitin ligase
@en
Crystal structure of mammalian ...... etitor of its ubiquitin ligase
@nl
prefLabel
Crystal structure of mammalian ...... etitor of its ubiquitin ligase
@ast
Crystal structure of mammalian ...... etitor of its ubiquitin ligase
@en
Crystal structure of mammalian ...... etitor of its ubiquitin ligase
@nl
P2093
P2860
P356
P1433
P1476
Crystal structure of mammalian ...... etitor of its ubiquitin ligase
@en
P2093
Ning Zheng
Shannon Nangle
Weiman Xing
P2860
P2888
P304
P356
10.1038/CR.2013.136
P577
2013-12-01T00:00:00Z
P5875
P6179
1007509475