Cks confers specificity to phosphorylation-dependent CDK signaling pathways - Wikidata - wikimedia - TriplyDB

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

http://www.wikidata.org/entity/Q27680509

about

Motif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulation Dual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1 Turnover of protein phosphorylation evolving under stabilizing selection An allosteric conduit facilitates dynamic multisite substrate recognition by the SCF(Cdc4) ubiquitin ligase Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes.Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.TORC1 coordinates the conversion of Sic1 from a target to an inhibitor of cyclin-CDK-Cks1.Regulation of cyclin-substrate docking by a G1 arrest signaling pathway and the Cdk inhibitor Far1.A docking interface in the cyclin Cln2 promotes multi-site phosphorylation of substrates and timely cell-cycle entry.Ultrasensitivity part II: multisite phosphorylation, stoichiometric inhibitors, and positive feedback.A Synthetic Dosage Lethal Genetic Interaction Between CKS1B and PLK1 Is Conserved in Yeast and Human Cancer Cells.Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection.The Prozone Effect Accounts for the Paradoxical Function of the Cdk-Binding Protein Suc1/Cks CDK1 structures reveal conserved and unique features of the essential cell cycle CDK.Core signalling motif displaying multistability through multi-state enzymes.Multisite phosphorylation networks as signal processors for Cdk1.Multistep phosphorylation systems: tunable components of biological signaling circuits.The G2 checkpoint-a node-based molecular switch.A genome-wide screen to identify genes controlling the rate of entry into mitosis in fission yeast Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability.CKS protein overexpression renders tumors susceptible to a chemotherapeutic strategy that protects normal tissues.Characterization of cyclin-dependent kinases and Cdc2/Cdc28 kinase subunits in Trichomonas vaginalis.2013: Signaling breakthroughs of the year.Homing in: Mechanisms of Substrate Targeting by Protein Kinases.CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein Ste5.Cyclin-dependent kinase 1-dependent activation of APC/C ubiquitin ligase.Structural insights into the functional diversity of the CDK-cyclin family

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P2860

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

http://www.wikidata.org/entity/Q27680509

description

2013 nî lūn-bûn

@nan

2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

@ast

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

@en

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

@nl

type

label

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

@ast

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

@en

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

@nl

prefLabel

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

@ast

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

@en

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

@nl

P1433

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Nature Structural & Molecular Biology

P1476

Cks confers specificity to phosphorylation-dependent CDK signaling pathways

@en

P2093

Alexander Hirschi

http://www.w3.org/2001/XMLSchema#string

Denise A McGrath

http://www.w3.org/2001/XMLSchema#string

Douglas R Kellogg

http://www.w3.org/2001/XMLSchema#string

Mardo Kõivomägi

http://www.w3.org/2001/XMLSchema#string

Mart Loog

http://www.w3.org/2001/XMLSchema#string

Michelle V Mai

http://www.w3.org/2001/XMLSchema#string

Seth M Rubin

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1

Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase

Two distinct mechanisms for negative regulation of the Wee1 protein kinase

An amplified sensitivity arising from covalent modification in biological systems

Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase

Ultrasensitivity in the Regulation of Cdc25C by Cdk1

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control

Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch

Crystal structure of the human cell cycle protein CksHs1: single domain fold with similarity to kinase N-lobe domain

P2888

P304

1407-1414

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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3213567

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P356

10.1038/NSMB.2707

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P433

12

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20

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Eva Rose M Balog

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2013-12-01T00:00:00Z

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258254137

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P6179

1020699294

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P698

24186063

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

structural biology

P932

4242096

http://www.w3.org/2001/XMLSchema#string