Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix
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Plasmodium falciparum CTP:phosphocholine cytidylyltransferase possesses two functional catalytic domains and is inhibited by a CDP-choline analog selected from a virtual screeningAlpha-synuclein function and dysfunction on cellular membranes.Molecular Mechanism for the Thermo-Sensitive Phenotype of CHO-MT58 Cell Line Harbouring a Mutant CTP:Phosphocholine CytidylyltransferaseTargeting Fat: Mechanisms of Protein Localization to Lipid DropletsLipid landscapes and pipelines in membrane homeostasis.PHOSPHATIDIC ACID PHOSPHOHYDROLASE Regulates Phosphatidylcholine Biosynthesis in Arabidopsis by Phosphatidic Acid-Mediated Activation of CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE Activity.Diacylglycerol Acyltransferase 1 Is Regulated by Its N-Terminal Domain in Response to Allosteric Effectors.From yeast to humans - roles of the Kennedy pathway for phosphatidylcholine synthesis.An auto-inhibitory helix in CTP:phosphocholine cytidylyltransferase hi-jacks the catalytic residue and constrains a pliable, domain-bridging helix pair.How CCTα puts a leash on phospholipid synthesis.Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis
P2860
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P2860
Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix
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2014 nî lūn-bûn
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2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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Structural Basis for Autoinhib ...... rane-binding Amphipathic Helix
@ast
Structural Basis for Autoinhib ...... rane-binding Amphipathic Helix
@en
Structural Basis for Autoinhib ...... rane-binding Amphipathic Helix
@nl
type
label
Structural Basis for Autoinhib ...... rane-binding Amphipathic Helix
@ast
Structural Basis for Autoinhib ...... rane-binding Amphipathic Helix
@en
Structural Basis for Autoinhib ...... rane-binding Amphipathic Helix
@nl
prefLabel
Structural Basis for Autoinhib ...... rane-binding Amphipathic Helix
@ast
Structural Basis for Autoinhib ...... rane-binding Amphipathic Helix
@en
Structural Basis for Autoinhib ...... rane-binding Amphipathic Helix
@nl
P2093
P2860
P921
P356
P1476
Structural Basis for Autoinhib ...... rane-binding Amphipathic Helix
@en
P2093
Bryan W Holland
D Peter Tieleman
Jaeyong Lee
Rosemary B Cornell
Svetla G Taneva
P2860
P304
P356
10.1074/JBC.M113.526970
P407
P577
2014-01-17T00:00:00Z